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Preliminary study on the mechanism of reading recovery in a pure alexia by using functional MRI
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIOLOGY
- Issue:
- 4
- DOI:
- 10.3760/j.issn:1005-1201.2004.04.020
- Key Word:
- 失读症;阅读;功能恢复;磁共振成像
Abstract： 目的利用磁共振功能成像(fMRI)技术观察阅读功能恢复过程中脑功能的变化,为阐明阅读和语言功能恢复机制提供实验依据.方法采用fMRI对1例汉语纯失读症患者在其发病后45 d和130 d分别进行扫描.在扫描过程中要求病人判断是否认识所呈现的3类汉字.经后处理获得脑激活图,并对2次实验所观察到的脑激活部位和激活体积等进行比较.结果第1次实验显示Broca区、Wernicke区和右侧纹外区等被激活.而在第2次实验中,除上述区域仍被激活外,病灶周围的左侧纹外区也见显著激活,且右侧纹外区的激活体积比首次实验增大了约2倍.结论左侧纹外区皮层是阅读功能
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