You Position: Home > Paper
Multislice spiral CT myocardial perfusion and coronary angiography in acute myocardial infarction:an experimental study
( views:311, downloads:154 )
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIOLOGY
- Issue:
- 3
- DOI:
- 10.3760/j.issn:1005-1201.2004.03.018
- Key Word:
- 心肌缺血;冠状动脉循环;体层摄影术,X线计算机;动物,实验
Abstract： 目的应用多层螺旋CT(MSCT)心肌灌注研究急性心肌缺血和梗死的灌注特点,探索MSCT冠状动脉造影对冠状动脉阻断的显示情况.方法健康杂种犬9只,于左冠状动脉前降支结扎前及结扎后30 min、和1、2、4、6、8 h不同时间分别行MSCT心肌灌注扫描,分析心肌在不同时期的灌注特点,并与病理检查结果对照.同时于左冠状动脉前降支结扎前及结扎后行MSCT冠状动脉造影,观察冠状动脉阻断的情况.结果犬心肌正常灌注量为(69.3±13.9) ml·100 g-1·min-1、达峰值时间为(12.8±2.1) s.左冠状动脉前降支结扎30 min后MSCT心肌灌注表现为灌注量减低,为 (25.2±3.4) ml·100g -1·min-1,时间-密度曲线低平,延迟10 min扫描左冠状动脉前降支供血区心肌密度为(67.1±11.4)HU,与正常心肌密度(44.9 ±22.0) HU比较差异无显著性意义(P>0.05).左冠状动脉前降支结扎4 h后,局部心肌呈明显延迟增强,为(82.1±15.2) HU.9只犬MSCT冠状动脉造影均显示结扎处左冠状动脉前降支中断.结论 MSCT心肌灌注结合冠状动脉造影可以判断心肌缺血和梗死,同时显示冠状动脉的阻塞状况.
- [1]刘远健,冯晓源,沈天真.电子束CT动态扫描检测心肌缺血状态的初步研究[J].1998,(2).
- [2]Klingenbeck Regn-K,Kopp AF,Baum U,etc.Subsecond multi-slice computed tomography: basics and applications.[J].1999,31(2).
- [3]A, Knez,C R, Becker,A, Leber,etc.Usefulness of multislice spiral computed tomography angiography for determination of coronary artery stenoses.[J].2001,88(10).
- [4]J A, Rumberger,M R, Bell.Measurement of myocardial perfusion and cardiac output using intravenous injection methods by ultrafast (cine) computed tomography.[J].1992,27 Suppl 2.
- [5]R, Rienmüller,C, Baumgartner,R, Kern,etc.[Quantitative determination of left ventricular myocardial perfusion with electron beam computerized tomography].[J].1997,22.
- [6]J R, Panting,A M, Taylor,P D, Gatehouse,etc.First-pass myocardial perfusion imaging and equilibrium signal changes using the intravascular contrast agent NC100150 injection.[J].1999,10(3).
- [7]刘玉清.心血管病影像诊断学[M].1900.