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Prevention and treatment of disseminated intravascular coagulation complicating intraarterial chemoembolization of hepatocellular carcinoma
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIOLOGY
- Issue:
- 11
- DOI:
- 10.3760/j.issn:1005-1201.2002.11.011
- Key Word:
- 癌,肝细胞;化学栓塞,治疗性;弥散性血管内凝血
Abstract： 目的探讨肝癌介入治疗后并发弥散性血管内凝血 (DIC) 的原因、预防措施、临床检查及治疗.方法原发性肝癌病人3例,均接受经导管肝动脉化疗栓塞治疗.结果 3例病人均出现穿刺点出血、血肿,静脉输液部位淤斑,1例伴口腔黏膜出血并颌下血肿.实验室检查显示血小板计数进行性下降,凝血酶原时间、激活的部分凝血活酶时间延长,纤维蛋白原降解产物、D-二聚体值升高.经治疗后,2例好转出院,1例因多器官功能衰竭而死亡.结论肝癌介入治疗后所发生的DIC是一种少见而严重的并发症,且死亡率较高.因此,对可疑凝血机制障碍的病人,在介入治疗前后应加强观察,及时进行实验室检查,以期早期发现,及时处理.
- [1]Timmerman JJ,ten Cate-H,Levi M.The pathophysiology of disseminated intravascular coagulation.[J].1999,82(2).
- [2]R L, Bick,J F, Strauss,E P, Frenkel.Thrombosis and hemorrhage in oncology patients.[J].1996,10(4).
- [3]邓家栋 ... [等]主编.邓家栋临床血液学[M].2001.
- [4]Mammen EF.Disseminated intravascular coagulation (DIC).[J].2000,13(4).
- [5]E F, Mammen.Coagulopathies of liver disease.[J].1994,14.
- [6]M J, Carey,G M, Rodgers.Disseminated intravascular coagulation: clinical and laboratory aspects.[J].1998,59(1).