You Position: Home > Paper
MRI study of neurofibromatosis type I
( views:108, downloads:616 )
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIOLOGY
- Issue:
- 4
- DOI:
- 10.3760/j.issn:1005-1201.2002.04.014
- Key Word:
- 磁共振成像;神经纤维瘤 I型
Abstract： 目的回顾神经纤维瘤病I型(NF1)患者MRI表现,分析MR扫描序列及其诊断价值,以建立合适的MR成像方案,为NF1影像诊断提供有价值的依据.方法对30例临床确诊为NF1患者采用本组MR成像方案进行扫描,主要包括:轴面SE序列T2WI;平扫矢状面SE脉冲序列T1WI;增强轴面或矢状面SE脉冲序列T1WI;轴面或冠状面液体衰减反转恢复(FLAIR)序列;同时分析病变的发病部位、数目、形态、信号的变化和病变的强化情况等.结果 MRI可见下列3种表现: (1)多发性脑内错构瘤:30例中25例在SE脉冲序列T2WI和FlAIR脉冲序列见高信号病灶,病灶主要位于苍白球、小脑和脑干.另外,25例中20例可见海马回、海马旁回等区晕状高信号改变.(2)视通道或下丘脑胶质瘤:视神经、视交叉增粗、扭曲;视交叉或下丘脑肿块,SE脉冲序列T2WI和FlAIR序列表现为不规则分叶状混杂信号肿块,在增强SE脉冲序列T1WI有明显不规则强化.(3)脊柱多发性神经纤维瘤:SE脉冲序列T2WI和脂肪抑制短时反转恢复(STIR)序列显示高信号沿脊神经分布的多发性肿瘤.结论 MRI能够作为1种常规的影像检查方法对NF1患者进行诊断和追踪.本组MR成像方案能较好地显示NF1的多发性或多灶性病变.
- [1]季洪兵,郑春雨,吴纪瑞,等.神经纤维瘤病的MRI诊断[J].2001,(5).
- [2]Byrd S,Ross BD,Darling C,etc.Short TE proton MRS and neurofibromatosis type 1 intracranial lesions.[J].1999,23(6).
- [3]R G, Curless,M, Siatkowski,J S, Glaser,etc.MRI diagnosis of NF-1 in children without café-au-lait skin lesions.[J].1998,18(3).
- [4]Moras P,Carollo C,Laverda A,etc.Spontaneous partial regression of low-grade glioma in children with neurofibromatosis-1: a real possibility.[J].1999,14(6).
- [5]G G, Massry,C F, Morgan,S M, Chung.Evidence of optic pathway gliomas after previously negative neuroimaging.[J].1997,104(6).
- [6]Rosenbaum T,Hoehn Berlage-M,van Dorsten-FA,etc.MRI abnormalities in neurofibromatosis type 1 (NF1): a study of men and mice.[J].1999,21(4).
- [7]陈孝柏,刘军,郭绍伦.多发性神经纤维瘤病的MRI诊断（附7例报告）[J].1994,(11).
- [8]Rossi LN,Triulzi F,Parazzini C,etc.Spontaneous improvement of optic pathway lesions in children with neurofibromatosis type 1.[J].1999,30(4).
- [9]Thakkar SD,Feigen U,Mautner VF.Spinal tumours in neurofibromatosis type 1: an MRI study of frequency, multiplicity and variety.[J].1999,41(9).
- [10]DiMario FJ Jr,Burleson JA,Ramsby GR.Brain morphometric analysis in neurofibromatosis 1 (see comments)[J].1999,56(11).