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The experimental study of treating the cystiform abdominal aneurysms by homemade TiNi shape memory mesh endovascular stents
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIOLOGY
- Issue:
- 3
- DOI:
- 10.3760/j.issn:1005-1201.2002.03.018
- Key Word:
- 主动脉瘤,腹;动物,实验;支架;放射学,介入性
Abstract： 目的研究、观察国产血管内支架治疗犬腹主动脉瘤的疗效.方法采用简单随机分组方法,将健康杂种犬32只随机分为4组,每组8只.组1:对照组,未置入支架;组2:实验组,腹主动脉前壁纵行切口长度≤1 cm,置入支架治疗;组3:实验组,腹主动脉前壁纵行切口长度>1 cm且≤2 cm,置入支架治疗;组4:实验组,腹主动脉前壁纵行切口长度≥3 cm,置入支架治疗.外科方法建立腹主动脉瘤模型后2周行介入治疗.术后每个月行增强CT检查;第6个月处死时,行腹主动脉造影检查.结果组1在6个月观察期内,CT和腹主动脉造影检查均示瘤腔存在.组2于第1个月CT检查时发现有1只犬瘤腔闭合;第2个月CT检查时有4只犬瘤腔闭合;第3个月有2只犬瘤腔闭合;第4个月有1只犬瘤腔闭合;第6个月腹主动脉造影检查也证实瘤腔闭合.组3 CT检查和腹主动脉造影检查发现每只犬均残留有1个小瘤腔,且瘤壁呈向心性增厚.组4 CT检查和腹主动脉造影检查发现每只犬均显示有1个大瘤腔.32只犬的腹主动脉均通畅.结论国产镍钛合金血管内裸支架,对瘤颈直径≤1 cm的腹主动脉瘤有治疗作用;对瘤颈直径>1 cm且≤2 cm者,可防止动脉瘤继续扩张和迟发破裂;对瘤颈直径≥3 cm者则无任何治疗作用.
- [1]C E, Ruiz,H P, Zhang,A I, Butt,etc.Percutaneous treatment of abdominal aortic aneurysm in a swine model: understanding the behavior of aortic aneurysm closure through a serial histopathological analysis.[J].1997,96.
- [2]Bernd Hagen,Bernd-M. Harnoss,Stephan Trabhardt,etc.Self-expandable macroporous nitinol stents for transfemoral exclusion of aortic aneurysms in dogs: Preliminary results[J].1993,16(6).
- [3]C E, Ruiz,H P, Zhang,J T, Douglas,etc.A novel method for treatment of abdominal aortic aneurysms using percutaneous implantation of a newly designed endovascular device.[J].1995,91.
- [4]王小祥,毛志远,曹征旺,等.TINI形状记忆合金腐蚀及细胞毒性的研究[J].1996,(4).