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间充质干细胞外泌体在女性生殖系统修复中的研究进展

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Author:: No author available

Journal Title:: Chinese Journal of Obstetrics and Gynecology

Issue:: 9

DOI:: 10.3760/cma.j.cn112141-20191205-00659

Key Word:: No keyword available

Abstract：外泌体作为间充质干细胞（MSC）旁分泌作用的主要方式之一，通过携带MSC内的多种核酸、蛋白质及脂质等成分，能够高效穿透多种生物屏障，改变靶细胞内的信号传导及基因表达情况，逐渐发展成一种高效的药物载体和基因治疗制剂。更重要的是，MSC外泌体能够模拟并发挥MSC的功能，有效促进组织再生能力，调节损伤局部的免疫反应，从而成为MSC治疗的潜在替代方案。目前，对于MSC外泌体在妇产科领域的基础研究也开始起步。本文聚焦MSC外泌体在女性生殖系统修复中的作用及其机制，并归纳分析其应用现状及研究进展。

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