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Fathoming of NIPT to further improve the efficiency of prenatal screening for birth defects
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- Author:
- No author available
- Journal Title:
- Chinese Journal of Obstetrics and Gynecology
- Issue:
- 2
- DOI:
- 10.3760/cma.j.issn.0529-567X.2020.02.006
- Key Word:
- No keyword available
Abstract： 无创产前检测（NIPT）是相对于侵入性产前诊断而言，无穿刺相关流产、感染等风险的产前筛查技术，很多学者及专业杂志均呼吁用游离DNA（cf-DNA）检测来描述通过母体血清中cf-DNA测序或比较基因组杂交技术筛查胎儿常见染色体非整倍体的检测。应强调在孕妇充分知情同意的前提下，可以有指征地选用cf-DNA检测进行产前筛查；在明确合理的成本-效益比前，不推荐在低风险孕妇中常规开展cf-DNA检测，并规范cf-DNA检测的临床服务流程。
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