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表没食子儿茶素没食子酸酯对雷公藤甲素诱导的大鼠卵巢颗粒细胞凋亡的保护作用
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- Author:
- No author available
- Journal Title:
- Chinese Journal of Obstetrics and Gynecology
- Issue:
- 11
- DOI:
- 10.3760/cma.j.issn.0529-567x.2017.11.012
- Key Word:
- No keyword available
Abstract： 颗粒细胞是卵巢的主要功能细胞,在卵泡发育中起着重要的作用.卵巢颗粒细胞的正常增殖与分化直接影响着卵泡的生长、发育、排卵、黄体形成以及激素分泌等卵巢的基本功能[1].卵巢颗粒细胞损伤会严重影响卵巢功能,甚至可能导致卵巢早衰.临床使用的一些抗肿瘤药物在发挥治疗作用的同时,具有细胞毒作用,可破坏正常的卵巢颗粒细胞,使其发生凋亡[2].
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