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Distribution and normal reference range of fetal nuchal translucency thickness in Kunming pregnant women in the first trimester

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Author:
No author available
Journal Title:
Chinese Journal of Obstetrics and Gynecology
Issue:
7
DOI:
10.3760/cma.j.issn.0529-567x.2012.07.009
Key Word:
颈部透明带检查;超声检查,产前;妊娠初期;参考值;Nuchal translucency measurement;Ultrasonography,prenatal;Pregnancy trimester,first;Reference values

Abstract´╝Ü Objective To establish the normal reference range of fetal nuchal translucency (NT) thickness in Kunming Chinese pregnant women in the first trimester.Methods The study samples comprised of 1790 Kunming pregnant women who attended antenatal visit in the first trimester in the First Affiliated Hospital of Kunming Medical University.The general information including maternal date of birth,past pregnant history and other related conditions were recorded.The crown rump length (CRL) and NT thickness at 11 - 13 +6 gestational weeks were measured according to guidelines from Fetal Medicine Foundation (FMF).Results The total 1790 of normal fetuses was recruited for final analysis.The mean and median values of CRL were (59.6 ± 9.2) mm and 58.3 mm,respectively.The mean and median values of NT thickness were (1.7 ± 0.5 ) mm and 1.7 mm,respectively.While the CRL were at between 45.0 - 54.9 mm,55.0 - 64.9 mm,65.0 - 74.9 mm and 75.0 - 84.0 mm,the corresponding values of NT thickness were 1.0 mm,1.3 mm,1.5 mm,1.5 mm at the 5th percentile and 2.0 mm,2.5 nun,2.7 mm,2.9 mm at the 95th percentile,respectively,and the corresponding medial values of NT thickness were 1.4 mm,1.7 mm,2.0 mm,2.0 mm,respectively.The NT thickness had no relationship with maternal age (P > 0.05).The mean value of NT thickness was ( 1.8 ± 1.1 ) mm in male fetuses.The mean value of NT thickness was ( 1.7 ±0.6) mm in female fetuses.The NT thickness in male fetuses was significantly thicker than that of females ( P = 0.001 ).Conclusion The present study established a reference range of normal fetal NT thickness corresponding with CRL in early pregnancy with reliable FMF quality control.

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