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卵巢癌OVCAR3细胞中CD+133细胞群的分离及其特性
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF OBSTETRICS AND GYNECOLOGY
- Issue:
- 7
- DOI:
- 10.3760/cma.j.issn.0529-567x.2011.07.017
- Key Word:
- No keyword available
Abstract： @@ 卵巢癌的病死率居妇科恶性肿瘤之首,5年生存率不足30%[1],其发生、发展机制尚不清楚.肿瘤干细胞理论认为,肿瘤中存在一小群具有自我更新和多向分化潜能的细胞,即肿瘤干细胞,可能是肿瘤转移和复发的根源[2].
- [1]Bonanno G,Procoli A,Rutella S.Cells with characteristics of cancer stem/progenitor cells express the CD133 antigen in human endometrial tumors.[J].2009,15(13).
- [2]T, Reya,S J, Morrison,M F, Clarke,etc.Stem cells, cancer, and cancer stem cells.[J].2001,414(6859).
- [3]Kondoh E,Mori S,Whitaker RS,etc.Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells.[J].2009,28(2).
- [4]Procoli A,Corallo M,Rutella S,etc.Expression of CD133-1 and CD133-2 in ovarian cancer.[J].2008,18(3).
- [5]Matei D,Zhang S,Chan MW,etc.Identification and characterization of ovarian cancer-initiating cells from primary human tumors.[J].2008,68(11).