You Position: Home > Paper
黄体生成素在辅助生殖技术促排卵周期中的应用
( views:373, downloads:241 )
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF OBSTETRICS AND GYNECOLOGY
- Issue:
- 7
- DOI:
- 10.3760/cma.j.issn.0529-567x.2010.07.020
- Key Word:
- No keyword available
Abstract： @@ 在女性的排卵周期中,卵泡的正常发育是由垂体分泌的卵泡刺激素(follicle stimulating hormone,FSH)和黄体生成素(luteinizing hormone,LH)两种激素控制的,两者对于正常卵泡雌二醇的生物合成都很重要,也就是所谓的"两种细胞,两种促性腺激素"学说,即FSH刺激卵泡发育,LH与卵泡膜细胞上的受体结合,激发雄激素前体从膜细胞转移至颗粒细胞,并通过FSH刺激芳香酶将雄激素转变为雌激素.
- [1]Balasch J,Carmona F,Fabregues F.Ovarian luteinizing hormone priming preceding follicle-stimulating hormone stimulation: clinical and endocrine effects in women with long-term hypogonadotropic hypogonadism.[J].2009,94(7).
- [2]Balasch J,Fabregues F.Is luteinizing hormone needed for optimal ovulation induction?[J].2002,14(3).
- [3]S C, Chappel,C, Howles.Reevaluation of the roles of luteinizing hormone and follicle-stimulating hormone in the ovulatory process.[J].1991,6.
- [4]E S, Sills,D P, Levy,M, Moomjy,etc.A prospective, randomized comparison of ovulation induction using highly purified follicle-stimulating hormone alone and with recombinant human luteinizing hormone in in-vitro fertilization.[J].1999,14.
- [5]Smith PC,Sluss PM,Jimenez Y,etc.Control of estradiol secretion in reproductive ageing.[J].2006,21(8).
- [6]B, Mannaerts,R, de Leeuw,J, Geelen,etc.Comparative in vitro and in vivo studies on the biological characteristics of recombinant human follicle-stimulating hormone.[J].1991,129.
- [7]Andersen CY,Andersen AN,Lossl K,etc.Androgen priming using aromatase inhibitor and hCG during early-follicular-phase GnRH antagonist down-regulation in modified antagonist protocols.[J].2006,21(10).
- [8]Rasmussen PE,Humaidan P,Bredkjaer HE,etc.Recombinant LH supplementation to recombinant FSH during the final days of controlled ovarian stimulation for in vitro fertilization. A multicentre, prospective, randomized, controlled trial.[J].2008,23(2).
- [9]E L, Yong,D T, Baird,R, Yates,etc.Hormonal regulation of the growth and steroidogenic function of human granulosa cells.[J].1992,74.
- [10]Robert Mitchell,Sally Hollls,Claire Rothwell,etc.Age related changes in the pituitary-testicular axis in normal men; lower serum testosterone results from decreased bioactive LH drive[J].1995,42(5).
- [11]Group T. E. R. H. L. S..Recombinant Human Luteinizing Hormone (LH) to Support Recombinant Human Follicle-Stimulating Hormone (FSH)-Induced Follicular Development in LH- and FSH-Deficient Anovulatory Women: A Dose-Finding Study[J].1998.
- [12]R, Fleming,F, Lloyd,M, Herbert,etc.Effects of profound suppression of luteinizing hormone during ovarian stimulation on follicular activity, oocyte and embryo function in cycles stimulated with purified follicle stimulating hormone.[J].1998,13.