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子宫内膜癌细胞中孕激素受体的甲基化对其表达及细胞生长的作用
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF OBSTETRICS AND GYNECOLOGY
- Issue:
- 4
- DOI:
- 10.3760/cma.j.issn.0529-567x.2009.04.015
- Key Word:
- No keyword available
Abstract： @@ 孕激素对子宫内膜正常功能的维持起着重要作用,孕激素通过与孕激素受体(progesterone receptor,PR)结合发挥作用.子宫内膜癌组织中PR的表达下调,不仅与子宫内膜癌的发生有关,而且还可能与肿瘤细胞的侵袭生长有关,最终可影响患者的预后及对激素治疗的反应,其表达下调的机制不清.
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