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子宫颈病变组织中PIK3CA mRNA的表达及其与人乳头状瘤病毒感染的关系
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF OBSTETRICS AND GYNECOLOGY
- Issue:
- 1
- DOI:
- 10.3760/cma.j.issn.0529-567x.2009.01.016
- Key Word:
- No keyword available
Abstract： @@ 宫颈癌是全球妇女中仅次于乳腺癌的第2位常见恶性肿瘤.实验室和流行病学研究表明,人乳头状瘤病毒(HPV)感染与宫颈癌有着密切的联系.磷脂酰肌醇-3激酶(PI3K)/蛋白激酶B(Akt)信号传导通路通过多方面的作用机制参与肿瘤发生、发展,其中作为PI3K催化亚单位的编码基因--PIK3CA基因在宫颈癌中的表达日益引起关注.
- [1]Garcia-Echeverria C,Sellers WR.Drug discovery approaches targeting the PI3K/Akt pathway in cancer.[J].2008,27(41).
- [2]Meng Q,Xia C,Fang J,etc.Role of PI3K and AKT specific isoforms in ovarian cancer cell migration, invasion and proliferation through the p70S6K1 pathway[J].2006,18(12).
- [3]Anna-Barbara, Moscicki.HPV Vaccines: today and in the Future.[J].2008,43(4 Suppl).