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临产前后产妇子宫平滑肌组织热休克蛋白70的表达化及其意义
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF OBSTETRICS AND GYNECOLOGY
- Issue:
- 9
- DOI:
- 10.3760/j.issn:0529-567X.2006.09.011
- Key Word:
- No keyword available
Abstract： @@ 分娩的发动与炎症因子有关[1].热休克蛋白70,既是分子伴侣,又是炎症因子--白细胞介素6(IL-6)、白细胞介素1β(IL-1β)的强力诱导剂和强效的免疫佐剂[2].研究证明,心肌组织中热休克蛋白27表达上调可导致心肌的收缩功能增强[3].为探讨子宫平滑肌组织中热休克蛋白70在临产前后的表达变化及其与分娩发动的关系,我们进行了研究,现将结果报道如下.
- [1]张卫社,陈亮香,伍招娣,等.不同药物对晚孕鼠子宫平滑肌及左心室心肌细胞电压依赖性钙通道-L亚型mRNA表达的影响[J].2003,(1).
- [2]Harrison JC,Sammut IA.Cardiac mitochondrial complex activity is enhanced by heat shock proteins.[J].2003,30(1).
- [3]Calderwood SK,Chen LB,Finberg RW,etc.HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine.[J].2000,6(4).
- [4]Bethin Kathleen E.,Nagai Yoshihiko,Sladek Robert,etc.Microarray Analysis of Uterine Gene Expression in Mouse and Human Pregnancy[J].2003.
- [5]Wetzka B,Deppert WR,Biller S,etc.Expression Patterns of CRH, CRH Receptors, and CRH Binding Protein in Human Gestational Tissue at Term.[J].2003,111(3).
- [6]White BG,Williams SJ,Highmore K,etc.Small heat shock protein 27 (Hsp27) expression is highly induced in rat myometrium during late pregnancy and labour[J].2005,129(1).
- [7]Brown KM,Papaconstantinou AD,Goering PL,etc.Regulation of uterine hsp90alpha, hsp72 and HSF-1 transcription in B6C3F1 mice by beta-estradiol and bisphenol A: involvement of the estrogen receptor and protein kinase C.[J].2003,144(2).
- [8]Matthews RC,Burnie JP.Human recombinant antibody to HSP90: a natural partner in combination therapy.[J].2005,5(4).