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Clinical significance of sentinel lymph nodes detection in patients with early stage cervical carcer
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF OBSTETRICS AND GYNECOLOGY
- Issue:
- 1
- DOI:
- 10.3760/j.issn:0529-567X.2004.01.005
- Key Word:
- 宫颈肿瘤;前哨淋巴结活组织检查;淋巴结切除术
Abstract： 目的评价前哨淋巴结(SLN)对早期宫颈癌盆腔淋巴结转移状况的预测价值,探讨检测SLN在指导早期宫颈癌盆腔淋巴清扫术中的意义.方法对2002年11月～2003年8月在山东省肿瘤医院手术治疗的23例早期宫颈癌患者行SLN检测,分别利用亚甲蓝和99mTc-硫胶体定位并原位切除SLN送快速冰冻病理检查,然后行经腹广泛全子宫切除+盆腔淋巴清扫术,比较SLN快速冰冻切片、SLN及其他盆腔淋巴结石蜡切片和抗角蛋白免疫组化染色结果.结果 23例患者中19例成功检测到SLN,共检出SLN 59枚,平均每例3枚,SLN检出率为83%(19/23).SLN活检术灵敏性为83%,特异性为100%,与病理检查结果符合率为95%.结论 SLN检测能较为准确地预测早期宫颈癌盆腔淋巴结的转移状况,但以SLN活检术替代传统的手术方式的可行性和安全性还需要更大样本量的前瞻性病例研究来进一步评价.
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