You Position: Home > Paper
胰岛素样生长因子1及胎盘生乳素与胎儿生长发育的关系
( views:195, downloads:52 )
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF OBSTETRICS AND GYNECOLOGY
- Issue:
- 12
- DOI:
- 10.3760/j.issn:0529-567X.2002.12.016
- Key Word:
- No keyword available
Abstract： @@ 在影响胎儿宫内生长发育的诸多因素中, 胰岛素样生长因子1(insulin-like growth factor-1, IGF-1)的作用尤为重要[1].有研究发现,在妊娠过程中,人类胎盘生乳素(human placental lactogen, hPL)可替代垂体生长激素,刺激IGF-1的产生,从而促进胎儿的生长[2].我们观察了妊娠期糖尿病(gestational diabetes mellitus, GDM)孕妇、胎儿生长受限(fetal growth restrict, FGR)孕妇和正常孕妇足月分娩时,母血、脐血中IGF-1、hPL的水平变化,及其与胎儿出生体重的关系,以探讨IGF-1、hPL在胎儿生长发育中的作用.
- [1]樊庆泊,边旭明,郎景和.胰岛素样生长因子与胎儿发育[J].1999,(4).
- [2]Langford,K,Nicolaides,K,Miell,JP.Maternal and fetal insulin-like growth factors and their binding proteins in the second and third trimesters of human pregnancy.[J].1998,13(5).
- [3]孙刚(医学).胎盘内分泌的基础与临床[M].2001.
- [4]Ostlund E,Bang P,Hagenas L,etc.Insulin-like growth factor I in fetal serum obtained by cordocentesis is correlated with intrauterine growth retardation.[J].1997,12(4).
- [5]A, Caufriez,F, Frankenne,G, Hennen,etc.Regulation of maternal IGF-I by placental GH in normal and abnormal human pregnancies.[J].1993,265(4 Pt 1).