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Clinical characteristics of clear cell carcinoma of the ovary
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF OBSTETRICS AND GYNECOLOGY
- Issue:
- 3
- DOI:
- 10.3760/j.issn:0529-567X.2002.03.012
- Key Word:
- 卵巢肿瘤;腺癌,透明细胞;药物疗法;存活率
Abstract： 目的探讨卵巢透明细胞癌的临床特点.方法将北京协和医院妇产科自1984年至2000年收治的43例卵巢透明细胞癌患者进行回顾性分析,并将卵巢透明细胞癌对化学药物治疗(化疗)的敏感性和生存率,与51例卵巢浆液性乳头状囊腺癌患者进行比较.结果卵巢透明细胞癌早期患者所占比例为14.4%,浆液性乳头状囊腺癌为3.8%,两者比较,差异有极显著性(P<0.005).行满意肿瘤细胞减灭术的晚期透明细胞癌化疗耐药型患者为88.9%,明显多于浆液性乳头状囊腺癌患者的57.1%;1年生存率(79.0%)明显低于浆液性乳头状囊腺癌患者(96.2%,P<0.01);行不满意肿瘤细胞减灭术的晚期透明细胞癌患者化疗耐药型的比例(83.3%)和生存率(71.4%)与浆液性乳头状囊腺癌患者(94.1%和85.1%)比较,差异均无显著性(P>0.05).结论卵巢透明细胞癌早期患者较多,易复发,预后差,应于术后进行以顺铂为主的化疗,并严密随诊.
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