Abstract： Patients with coronary artery disease (CAD),after first percutaneous coronary intervention (PCI),often need repeat unplanned percutaneous revascularization due to plaque progression in culprit or non-culprit lesions,including target lesion revascularization (TLR),target vessel revascularization (TVR),and other vessel revascularization (OVR).[1] Low-density lipoprotein cholesterol (LDL-C) levels are controllable and its reduction is integral to reducing major adverse cardiac events after PCI.In this study,active lipid-lowering therapy was widely appreciated early after coronary stenting,showing an initial decline in levels of LDL-C,while its emphasis and recognition was attenuated over time with an increased risk of revascularization due to higher levels of LDL-C.