Abstract： To the Editor:A 48-year-old Chinese woman complained of chest tightness,shortness of breath,and palpitations for 8 months.These symptoms were gradually increasing and the edema on both lower limbs appeared l month ago.She had a history of uterine fibroids.Sound of tumor fluttering was heard at the 3/4th intercostal space of the left libs;at the same time,systolic murmur was heard at the apical area.Cardiac ultrasound of another hospital indicated a mass of right atrium which was diagnosed as myxoma.Cardiac ultrasound imaging showed that inferior vena cava and right heart cavity were occupied by a mass [Figure 1a].Computed tomography angiography (CTA) of the abdomen and heart demonstrated that there were multiple irregular soft-tissue masses in uterus,which entered the inferior vena cava through the right ovarian vein and finally reached the right atrium [Figure lb,1c].Radiologists considered the disease as uterine leiomyomatosis (UL) and proposed to check through magnetic resonance imaging (MRI).According to MRI of the abdomen [Figure 1d,1e] and heart [Figure lf],as well as diffusion-weighted imaging (DWI) [Figure 1g],the disease was diagnosed as UL.Such diagnosis was confirmed by surgery and pathology [Figure 1h].The above symptoms were significantly alleviated after operation,and edema of both lower limbs disappeared 10 days after operation.