Diagnostic performance of magnetic resonance venography in the detection of recanalization in patients with chronic cerebral venous sinus thrombus
- Author:
- No author available
- Journal Title:
- CHINESE MEDICAL JOURNAL
- Issue:
- 20
- DOI:
- 10.3760/cma.j.issn.0366-6999.2009.20.006
- Key Word:
- venous sinus thrombosis;cranial;magnetic resonance venography;angiography;digital subtraction
Abstract： Background In the chronic stage of cerebral venous sinus thrombosis (CVST), recanalization can result in disparate MR appearances. We aimed to prospectively investigate the diagnostic accuracy of magnetic resonance venography (MRV) in the evaluation of the recanalization of CVST.Methods This study prospectively evaluated the diagnostic performance of 2-dimensional time-of-flight (2D-TOF) MRV in thirty-two consecutive patients during a three- to six-month follow-up for CVST. Both 2D-TOF MRV and digital substraction angiography (DSA) were undertaken. Diagnostic accuracy of 2D-TOF MRV in the detection of recanalized thrombus was evaluated using DSA as the reference standard.Results MRV and DSA were completed without complications in all 32 patients. The sensitivity, specificity, positive predictive value, and negative predictive value of 2D-TOF MRV for the detection of recanalization on a segmental basis were 91% (62/68), 93% (37/40), 95% (62/65), and 86% (37/43) respectively.Conclusion 2D-TOF MRV provides high sensitivity and specificity for the diagnosis of recanalized CVST segments.
- [1]C. MICHEL HARPER Jr.,BRIAN P. O'NEILL,J. DESMOND O'DUFFY,etc.Intracranial Hypertension in Behçet's Disease: Demonstration of Sinus Occlusion With Use of Digital Subtraction Angiography[J].1985,60(6).
- [2]Scott JN,Montanera WJ,Willinsky RA,etc.Intracranial venous system: gadolinium-enhanced three-dimensional MR venography with auto-triggered elliptic centric-ordered sequence--initial experience.[J].2003,226(1).
- [3]Kallmes DF,White JB,Kaufmann TJ.Venous sinus thrombosis: a misdiagnosis using MR angiography.[J].2008,8(2).
- [4]D, Dormont,R, Anxionnat,S, Evrard,etc.MRI in cerebral venous thrombosis.[J].1994,21.
- [5]J L, Leach,M, Wolujewicz,W M, Strub.Partially recanalized chronic dural sinus thrombosis: findings on MR imaging, time-of-flight MR venography, and contrast-enhanced MR venography.[J].2007,28(4).
- [6]Reyes T,Ison C,Chia J,etc.Cerebral MR venography in children: comparison of 2D time-of-flight and gadolinium-enhanced 3D gradient-echo techniques.[J].2005,235(3).
- [7]H P Mattle,K U Wentz,R R Edelman,etc.Cerebral venography with MR.[J].1991,178(2).
- [8]Kirchhof K,Sartor K,Jansen O,etc.More Reliable Noninvasive Visualization of the Cerebral Veins and Dural Sinuses: Comparison of Three MR Angiographic Techniques.[J].2002,224(3).
- [9]Jan, Stam.Cerebral venous and sinus thrombosis: incidence and causes.[J].2003,92.
- [10]Bousser M. G.,Chiras J.,Bories J.,etc.Cerebral venous thrombosis--a review of 38 cases[J].1985.
- [11]Studer A,Georgiadis D,Baumgartner RW,etc.Recanalisation of cerebral venous thrombosis.[J].2003,74(4).
- [12]D J, Rippe,O B, Boyko,C E, Spritzer,etc.Demonstration of dural sinus occlusion by the use of MR angiography.[J].1900,11(1).
- [13]Stolz E,Gerriets T,Kaps M,etc.Influence of recanalization on outcome in dural sinus thrombosis: a prospective study.[J].2004,35(2).
- [14]H, Mattle,R R, Edelman,M A, Reis,etc.Flow quantification in the superior sagittal sinus using magnetic resonance.[J].1990,40.
- [15]D, Dormont,K, Sag,A, Biondi,etc.Gadolinium-enhanced MR of chronic dural sinus thrombosis.[J].1900,16(6).