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Induction of lupus-like renal damages by double stranded DNA derived from Trypanosoma equiperdum
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- Author:
- No author available
- Journal Title:
- CHINESE MEDICAL JOURNAL
- Issue:
- 20
- DOI:
- No doi available
- Key Word:
- DNA,double-stranded;antinuclear antibody;lupus nephritis;models,animal
Abstract： @@ Lupus nephritis is the most common visceral complication in the patients with systemic lupus erythematosus (SLE).1 It was evident that the anti-dsDNA antibodies were closely related to lupus nephritis, as seen in patients who had higher titers of serum anti-dsDNA antibodies had more severe renal lesions and even worse prognosis.2 So far it is still unknown how the dsDNA or anti-dsDNA antibody plays a role in the pathogenesis of lupus nephritis.
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