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Advances in autophagy in diabetic peripheral neuropathy

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Author:
No author available
Journal Title:
Chinese Journal of Diabetes
Issue:
1
DOI:
10.3969/j.issn.1006-6187.2023.01.016
Key Word:
自噬;糖尿病周围神经病变;神经损伤

Abstract´╝Ü 糖尿病周围神经病变(DPN)机制复杂,是糖尿病神经性疼痛主要原因.自噬是一种细胞内分解代谢过程,通过实现细胞本身代谢需要和某些细胞器更新维持细胞内环境稳态.自噬通过参与氧化应激、内质网应激、雪旺细胞内损伤髓鞘清除及炎症小体活化,影响DPN发生发展.本文对DPN中细胞自噬的研究进展进行综述.

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