You Position: Home > Paper

Research progress in the regulation of islet α cell proliferation

( views:11, downloads:6 )
Author:
No author available
Journal Title:
Chinese Journal of Diabetes
Issue:
1
DOI:
10.3969/j.issn.1006-6187.2023.01.014
Key Word:
胰岛α细胞;胰高血糖素;细胞增殖;糖尿病;药物治疗

Abstract´╝Ü 胰高血糖素(GCG)作为胰岛素拮抗调节激素,在DM发生发展中起重要作用.目前部分阻断GCG受体药物已完成T2DM患者Ⅱ期临床试验,降糖效果良好.动物研究中阻断GCG信号通路后胰岛α细胞异常增殖,靶向GCG信号通路疗效仍存争议.本文对胰岛α细胞增殖调控的研究进展进行综述.

WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn