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Correlation between body mass index, serum triglyceride and painful diabetic neuropathy
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- Author:
- No author available
- Journal Title:
- Chinese Journal of Diabetes
- Issue:
- 1
- DOI:
- 10.3969/j.issn.1006-6187.2023.01.007
- Key Word:
- 体重指数;甘油三酯;痛性糖尿病神经病变;糖尿病周围神经病变
Abstract： 目的 探讨T2DM患者BMI和血清TG与痛性糖尿病神经病变(PDN)的相关性.方法 选取2017年12月至2020年6月于宁夏医科大学总医院内分泌科住院治疗的T2DM患者600例,根据糖尿病周围神经病变(DPN)诊断标准和神经性疼痛问卷分为单纯T2DM组(T2DM,n=155)、DPN组(n=234)和PDN组(n=211).比较各组BMI、TG等.结果 T2DM、DPN、PDN组BMI、TG依次升高(P<0.05).Spearman相关分析显示,BMI与24 hUAlb呈正相关(P<0.05),TG与TC、24 hUAlb呈正相关(P<0.05).Logistic回归分析显示,BMI、TG、DM病程、24 hUAlb是PDN的影响因素.受试者工作特征(ROC)曲线分析显示,BMI、TG诊断PDN的敏感度为69.2％、68.7％,特异度为85.9％、86.3％,ROC曲线下面积(AUC)为0.825、0.826(P<0.01).BMI、TG联合检测的AUC为0.908(P<0.01).结论 BMI和血清TG升高是PDN的影响因素,体育锻炼及降脂药物使用可能为治疗PDN提供新思路.
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