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Values of hemoglobin glycation index and urine albumin/creatinine ratio changes in patients with type 2 diabetic retinopathy
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- Author:
- No author available
- Journal Title:
- Chinese Journal of Diabetes
- Issue:
- 11
- DOI:
- 10.3969/j.issn.1006⁃6187.2022.11.003
- Key Word:
- 糖尿病,2型;糖尿病视网膜病变;血红蛋白糖化指数
Abstract： 目的 探讨DR患者血红蛋白糖化指数(HGI)和UACR变化的意义.方法 选取2019年1月至2020年12月于宿迁市第一人民医院内分泌科住院的T2DM患者268例.根据眼底检查结果分为单纯T2DM组(T2DM,n=159)及T2DM合并DR组(DR,n=109).根据FPG和HbA1c计算HGI,定义HGI≥0为高水平,HGI<0为低水平.比较两组一般资料和实验室生化指标,分析DR的危险因素;比较两组高HGI、UACR发生率及HGI+UACR对DR的诊断价值.结果 Logistic回归分析结果显示,HGI、UACR是DR的危险因素.DR组高HGI、高UACR发生率高于T2DM组(P<0.05).受试者工作特征(ROC)曲线分析显示,HGI+UACR可有效预测DR,ROC曲线下面积为0.76(P<0.01).结论 HGI与UACR与DR发病密切相关,对DR有一定预测价值,HGI联合UACR可用于DR个性化评估和风险预测.
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