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长链非编码RNA在急性心肌梗死中的作用及生物学机制的研究进展

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Author:: No author available

Journal Title:: China Clinical Practical Medicine

Issue:: 4

DOI:: 10.3760/cma.j.cn115570-20200407-00445

Key Word:: 长链非编码RNA;急性心肌梗死;心肌细胞凋亡;炎症反应;血管生成;纤维化重塑

Abstract：越来越多的研究表明长链非编码RNA通过调节心肌细胞凋亡、炎症反应、血管生成、心肌细胞纤维化重塑等生理病理过程在急性心肌梗死中发挥重要作用。本文对长链非编码RNA在急性心肌梗死中的研究进展进行综述，旨在为急性心肌梗死的临床诊断及治疗提供新思路。

Reference

[1]Orogo, Amabel M.,Gustafsson, Asa B..Cell death in the myocardium: My heart won't go on[J].2013,65(8).
[2]Ji Ping,Diederichs Sven,Wang Wenbing,etc.MALAT-1, a novel noncoding RNA, and thymosin β4 predict metastasis and survival in early-stage non-small cell lung cancer[J].2003,22(39).
[3]L, Li,J-J, Wang,H-S, Zhang.LncRNA-CARl in a rat model of myocardial infarction.[J].2018,22(13).
[4]Bountali, Aikaterini,Tonge, Daniel P.,Mourtada-Maarabouni, Mirna.RNA sequencing reveals a key role for the long non-coding RNA MIAT in regulating neuroblastoma and glioblastoma cell fate[J].2019,130.
[5]Norifumi Takeda,Ichiro Manabe.Cellular Interplay between Cardiomyocytes and Nonmyocytes in Cardiac Remodeling[J].2011,2011.
[6].Non-coding RNA[J].2006,15(suppl_1).
[7].Long Noncoding RNA Highly Upregulated in Liver Cancer Regulates the Tumor Necrosis Factor-α-Induced Apoptosis in Human Vascular Endothelial Cells[J].2016,(6).
[8]Huang Songqun,Zhang Liang,Song Jingwen,etc.Long noncoding RNA MALAT1 mediates cardiac fibrosis in experimental postinfarct myocardium mice model[J].2019,234(3).
[9]Ye Zi-ming,Yang Shuai,Xia Yuan-peng,etc.LncRNA MIAT sponges miR-149-5p to inhibit efferocytosis in advanced atherosclerosis through CD47 upregulation[J].2019,10(2).
[10]Kaili,Hao,Wei,Lei,Hongchun,Wu,etc.LncRNA-Safe contributes to cardiac fibrosis through Safe-Sfrp2-HuR complex in mouse myocardial infarction.[J].2019,9(24).
[11]Bo&#x2010,fang Zhang,Hong Jiang,etc.LncRNA H19 ameliorates myocardial infarction‐induced myocardial injury and maladaptive cardiac remodelling by regulating KDM3A[J].2020,24(1).
[12]Franziska Kenneweg,Claudia Bang,Ke Xiao,etc.Long Noncoding RNA-Enriched Vesicles Secreted by Hypoxic Cardiomyocytes Drive Cardiac Fibrosis[J].2019,18.
[13]Guoqiang Sun,Yubo Li,Zhiyong Ji.Up-regulation of MIAT aggravates the atherosclerotic damage in atherosclerosis mice through the activation of PI3K\/Akt signaling pathway[J].2019,26(1).
[14]Zhou Xue‐liang,Zhu Rong‐rong,Liu Sheng,etc.Notch signaling promotes angiogenesis and improves cardiac function after myocardial infarction[J].2018,119(8).
[15]Shi, Hao-Jie,Wang, Ming-Wei,Sun, Jia-Teng,etc.A novel long noncoding RNA FAF inhibits apoptosis via upregulating FGF9 through PI3K/AKT signaling pathway in ischemia-hypoxia cardiomyocytes[J].2019,234(12 Pt.1).
[16]Bo Long,Na Li,Xi-Xia Xu,etc.Long noncoding RNA FTX regulates cardiomyocyte apoptosis by targeting miR-29b-1-5p and Bcl2l2[J].2018,495(1).
[17]Li X.,·Zhou J..Inhibition of the lncRNA Mirt1 Attenuates Acute Myocardial Infarction by Suppressing NF-κB Activation[J].2017,42(3).
[18]Xiaoyan Guo,Xiaoguang Wu,Yan Han,etc.LncRNA MALAT1 protects cardiomyocytes from isoproterenol‐induced apoptosis through sponging miR‐558 to enhance ULK1‐mediated protective autophagy[J].2019,234(7).
[19]Boon, Reinier A.,Jae, Nicolas,Holdt, Lesca,etc.Long Noncoding RNAs From Clinical Genetics to Therapeutic Targets?[J].2016,67(10).
[20]Shan K,Jiang Q,Wang X -Q,etc.Role of long non-coding RNA-RNCR3 in atherosclerosis-related vascular dysfunction[J].2016,7(6).
[21]Hanyu,Shi,Zhenhua,Dong,Haiqing,Gao.LncRNA TUG1 protects against cardiomyocyte ischaemia reperfusion injury by inhibiting HMGB1.[J].2019,47(1).
[22].An integrated encyclopedia of DNA elements in the human genome[J].2012,489(7414).
[23]Lu, Qing,Meng, Qingyu,Qi, Mingran,etc.Shear-Sensitive lncRNA AF131217.1 Inhibits Inflammation in HUVECs via Regulation of KLF4[J].2019,73(5).
[24]Hao, Shuang,Liu, Xiaokang,Sui, Xin,etc.Long non-coding RNA GAS5 reduces cardiomyocyte apoptosis induced by MI through sema3a[J].2018,120(Pt.A).
[25]Cai, Benzhi,Ma, Wenya,Bi, Chongwei,etc.Long noncoding RNA H19 mediates melatonin inhibition of premature senescence of c-kit(+) cardiac progenitor cells by promoting miR-675[J].2016,61(1).
[26]Wang, Yanbin,Yang, Xudong,Jiang, An,etc.Methylation-dependent transcriptional repression of RUNX3 by KCNQ1OT1 regulates mouse cardiac microvascular endothelial cell viability and inflammatory response following myocardial infarction[J].2019,33(12).
[27]Xueling Li,Jinxuan Zhao,Jin Geng,etc.Long non‐coding RNA MEG3 knockdown attenuates endoplasmic reticulum stress‐mediated apoptosis by targeting p53 following myocardial infarction[J].2019,23(12).