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经颅磁刺激治疗卒中后抑郁机制的研究进展

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Author:: No author available

Journal Title:: China Clinical Practical Medicine

Issue:: 6

DOI:: 10.3760/cma.j.issn.1673-8799.2019.06.020

Key Word:: 非侵入性大脑刺激技术;经颅磁刺激;卒中后抑郁;机制

Abstract：卒中后抑郁(PSD)是一种神经精神疾病,可以在脑卒中后出现,与未患有抑郁症的脑卒中患者相比,PSD患者的功能和恢复效果较差,在PSD患者中,自杀的风险也更高. PSD可能与复杂的病理生理机制有关,包括心理和精神方面的问题,这些问题与功能缺陷和脑损伤的神经化学变化有关.经颅磁刺激是一种非侵入性的方法,通过对大脑的磁刺激来研究皮质兴奋性,磁刺激是一种较有价值的方法,可以帮助了解PSD的病理生理学.尽管重复的磁刺激对PSD患者可以有效的治疗,但作用机制仍然是未知的.本文回顾了现有的有关重复磁刺激的已知机制,以期更好地理解PSD相关的病理生理学,在考虑使用重复磁刺激作为PSD的治疗方法时应该会有所帮助.

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