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Effect of Xuebijing on inflammatory factor of lung injury after traumatic brain injury

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Author:
No author available
Journal Title:
China Clinical Practical Medicine
Issue:
1
DOI:
10.3760/cma.j.issn.1673-8799.2018.01.021
Key Word:
血必净;创伤性脑损伤后肺损伤;临床价值;Xuebijing;Lung injury after traumatic brain injury;Clinical value

Abstract´╝Ü Objective To investigate the application value of Xuebijing in treatment of lung injury after traumatic brain injury. Methods A total of 90 rats with traumatic brain injury models were estab-lished and randomly divided into the physiological saline group,TBI model group and Xuebijing intervention group,with 30 cases in each group. The inflammatory factor C-reactive protein was statistically significantly analyzed. Results After 24 hours of treatment,the inflammatory factor C-reactive protein in the physiologi-cal saline group,TBI model group and Xuebijing intervention group were(64. 42 ± 13. 22)mg/L,(63. 85 ± 14. 36)mg/L and(63. 83 ± 13. 51) mg/L,and there was no statistically significant difference between the three groups( P >0. 05 ) . The inflammatory factor C-reactive protein in the Xuebijing intervention group were(31.52 ±10.02)mg/L at Day 7,(21.35 ±9.54)mg/L at Day 14 and(13.14 ±3.06)mg/L at Day 21,which were significantly better than those in the physiological saline group and TBI model group( P<0. 05). Conclusion Xuebijing in treatment of lung injury after trauma brain injury can significantly im-prove the level of inflammatory factor C-reactive protein,which is worth to be clinical promoted.

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