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多囊卵巢伴非酒精性脂肪肝的卵巢超声特征及性激素水平改变
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- Author:
- No author available
- Journal Title:
- China Clinical Practical Medicine
- Issue:
- 3
- DOI:
- 10.3760/cma.j.issn.1673-8799.2017.03.013
- Key Word:
- 多囊卵巢综合征;非酒精性脂肪肝;超声;性激素
Abstract： 目的 探讨多囊卵巢综合征(PCOS)伴非酒精性脂肪肝(NAFLD)患者的卵巢超声特征及性激素6项指标的改变,分析PCOS伴不同程度的NAFLD与卵巢形态、功能改变的相关性.方法 选取2013年7月至2016年6月福建中医药大学附属人民医院妇科收治的99例PCOS伴NAFLD患者,根据肝脏的超声检查结果分为轻、中、重度脂肪肝3组.所有患者双侧卵巢呈多囊改变,对3组患者卵巢体积、卵泡数、卵泡最大直径、卵巢间质血流最大流速、卵巢间质血流阻力指数及性激素指标进行统计学分析.结果 随着3组患者脂肪肝程度加重,卵巢体积增大、卵泡数增多、卵泡最大直径减小、间质血流速度增高、间质血流阻力指数减少,3组比较差异有统计学意义(P<0.05),重度脂肪肝组卵巢间质血流为高速低阻,差异有统计学意义(P<0.05);随着脂肪肝程度加重,3组患者的总睾酮(TT)增高,促卵泡生成素(FSH)浓度减低,差异有统计学意义(P<0.05).黄体生成素(LH)、促黄体生成素与促卵泡生成素的比值(LH/FSH)、雌二醇(E2)和泌乳素(PRL)比较,差异无统计学意义(P>0.05).结论 PCOS伴NAFLD患者各组间卵巢超声特征及性激素水平具有一定的差异,考虑PCOS患者的脂代谢异常可能影响卵巢的形态及功能,对于PCOS伴NAFLD患者应同时积极进行降脂治疗.
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