Abstract： ObjectiveTo summarize clinical effect and experience for surgical treatment in off-pump coronary artery bypass in 128 patients.Methods128 cases of age older than 60 years with Coronary heart disease (CHD) undergoing surgical repair in off-pump coronary artery bypass from October 2013 to June 2016 were analyzed retrospectively in our department. All the patients received surgical repair in off-pump coronary artery bypass under general anesthesia by the sternum midline incision line. Summary the complications following surgery.Results Surgical operations were performed in all patients and no death occurred during surgery.The perioperative complications after surgery: low cardiac syndrome (3 cases), arrhythmia(7 cases),including supraventricular tachicardia(2cases),complete atrioventricular block (1 cases), atrial fibrillation(4 cases); pulmonary infection with hypoxemia(5 cases).Secondary endotracheal intubation (2 cases),pleural effusion(3 case),atelectasis (2 cases), kidney injury(1 case),brain injury(1 case). The average drainage of chest was 350 ml, the time for making use of respirometer was (10.12±3.46) h, the length of hospital stay was (10±6) d. All patients were followed up from 3 months to 3 years.As a result,postoperative cardiac function improved significantly.Conclusions Surgical repair in off-pump coronary artery bypass for older patients with Coronary heart disease is safe and effective, surgical technical experience accumulation and the improvement of postoperative care can help to further reduce the incidence of complications.