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胰岛素样生长因子结合蛋白-3在糖和脂肪代谢中的作用

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Author:: No author available

Journal Title:: China Clinical Practical Medicine

Issue:: 6

DOI:: 10.3760/cma.j.issn.1673-8799.2015.06.031

Key Word:: 胰岛素样生长因子结合蛋白-3;胰岛素抵抗;脂肪细胞;代谢

Abstract：胰岛素样生长因子结合蛋白-3（IGFBP-3）可通过与胰岛素样生长因子结合和抑制细胞增殖的独立方式调节胰岛素样生长因子的功能。虽然最近的研究发现IGFBP-3也具有代谢调节作用，但其在糖和脂肪组织代谢中的确切作用却知之甚少。笔者现对IGFBP-3在葡萄糖和脂质代谢中的生物学作用进行综述。

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