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Severe acute pancreatitis: mediate between hemostasis and anticoagulation

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Author:: No author available

Journal Title:: Chinese Journal of Pancreatology

Issue:: 3

DOI:: 10.3760/cma.j.cn115667-20220322-00039

Key Word:: 重症急性胰腺炎;内脏静脉血栓;全身炎症反应;抗凝治疗;止血

Abstract：重症急性胰腺炎患者胰腺组织的病理表现多为出血和坏死，其伴发的全身炎症反应综合征又常导致血液处于高凝状态，增加内脏静脉血栓形成的风险，加重多器官功能损伤。如何妥善处理胰腺局部止血与全身抗凝的治疗矛盾，目前尚无共识意见。本文系统阐述了胰腺坏死出血和内脏静脉血栓的病理生理机制及临床特征，对临床医师在治疗重症急性胰腺炎时采用止血与抗凝措施提出了探索性意见。

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