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重症急性胰腺炎的免疫紊乱与免疫治疗进展
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- Author:
- No author available
- Journal Title:
- Chinese Journal of Pancreatology
- Issue:
- 5
- DOI:
- 10.3760/cma.j.issn.1674-1935.2014.05.022
- Key Word:
- No keyword available
Abstract： 重症急性胰腺炎(severe acute pancreatitis,SAP)是临床上常见的急腹症,起病急,病程快,病情凶险,早期即可发生全身炎症反应综合征(systemic inflammatory response syndrome,SIRS)和多器官功能障碍综合征(multiple organ dysfunction syndrome,MODS),病死率高达20％～30％[1].迄今为止,SAP发病的确切机制尚未完全阐明.传统的酶异常激活理论和自身消化学说己不能全面解释SAP的发病机制及其复杂的病理进程.近期研究表明,免疫功能紊乱在SAP病理生理机制中的作用受到广泛关注.
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