You Position: Home > Paper
囊液分析在胰腺囊性病变鉴别诊断中的价值
( views:340, downloads:165 )
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF PANCREATOLOGY
- Issue:
- 2
- DOI:
- 10.3760/cma.j.issn.1674-1935.2007.02.021
- Key Word:
- No keyword available
Abstract： @@ 胰腺囊性病变包括假性囊肿(pseudocysts, PC)和囊性肿瘤.近些年由于CT影像技术的发展,胰腺囊性病变的诊断率明显提高.胰腺囊性肿瘤仅占胰腺囊肿的10% ～ 15%[1],但种类繁多,并且具有良性、交界性及恶性的不同程度分化,其中最常见的病变类型为:浆液性囊腺瘤(serous cystade-nomas,SCA)占32% ～ 39%;黏液性囊性肿瘤包括黏液性囊腺瘤(mucinous cystic adenomas,MCA)和黏液性囊腺癌(mucinous cystadenocarcinoma, MCAC),共占10% ～ 45%;导管内乳头状黏液瘤(intraductal papillary mucinous neoplasms,IPMN)占21% ～ 33%[2-3].假性囊肿和浆液性囊腺瘤为良性病变,无症状者不必行手术治疗;而黏液性囊性肿瘤和导管内乳头状瘤具有潜在的恶性,无论是否有症状均应行手术治疗.因此,术前确定胰腺囊性病变的性质非常重要,这对选择合适的治疗方案及手术方式具有指导意义.随着内镜超声(EUS)技术的成熟,通过EUS引导下细针穿刺(FNA)只要取得2 ml囊液,就可对囊液中的肿瘤标志物、胰酶、粘蛋白和细胞等成分进行检测,为判断胰腺囊性病变的性质提供依据.
- [1]C, Sperti,C, Pasquali,P, Guolo,etc.Serum tumor markers and cyst fluid analysis are useful for the diagnosis of pancreatic cystic tumors.[J].1996,78(2).
- [2]Kim YT,Han JK,Ryu JK,etc.Cyst fluid analysis for the differential diagnosis of pancreatic cysts.[J].2004,31(2).
- [3]Brown N,Vogt DP,Henderson JM,etc.Natural history of indeterminate pancreatic cysts.[J].2005,138(4).
- [4]Pascal Hammel,Philippe Levy,Hélène Voitot,etc.Preoperative cyst fluid analysis is useful for the differential diagnosis of cystic lesions of the pancreas[J].1995,108(4).
- [5]Lim SJ,Alasadi R,Wayne JD,etc.Preoperative evaluation of pancreatic cystic lesions: cost-benefit analysis and proposed management algorithm.[J].2005,138(4).
- [6]Adsay NV,Compton CC,Klimstra DS.Cystic lesions of the pancreas. Introduction.[J].2000,17(1).
- [7]A L, Warshaw,P L, Rutledge.Cystic tumors mistaken for pancreatic pseudocysts.[J].1987,205.
- [8]Laurens A, van der Waaij,Hendrik M, van Dullemen,Robert J, Porte.Cyst fluid analysis in the differential diagnosis of pancreatic cystic lesions: a pooled analysis.[J].2005,62(3).