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胰腺癌组织中nm23和PCNA的表达及临床意义
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF PANCREATOLOGY
- Issue:
- 1
- DOI:
- 10.3760/cma.j.issn.1674-1935.2007.01.015
- Key Word:
- No keyword available
Abstract： @@ 胰腺癌发病隐匿,恶性程度高,早期诊断困难,并且对各种辅助治疗敏感性不高[1],生存率低,是预后差的恶性肿瘤之一[2].为探讨胰腺癌生物学行为与nm23和PCNA表达的关系,本实验应用免疫组织化学PV-9000通用型二步法检测41例胰腺癌组织中nm23和PCNA的表达情况,并探讨二者的表达与病理学分级、临床分期之间的关系.
- [1]G, Ohshio,T, Imamura,N, Okada,etc.Immunohistochemical expression of nm23 gene product, nucleotide diphosphate kinase, in pancreatic neoplasms.[J].1997,22.
- [2]R H, Hawes,Q, Xiong,I, Waxman,etc.A multispecialty approach to the diagnosis and management of pancreatic cancer.[J].2000,95(1).
- [3]J A Martinez,S Prevot,B Nordlinger,etc.Overexpression of nm23-H1 and nm23-H2 genes in colorectal carcinomas and loss of nm23-H1 expression in advanced tumour stages.[J].1995,37(5).
- [4]Neoptolemos JP,Dunn JA,Stocken DD,etc.Adjuvant chemoradiotherapy and chemotherapy in resectable pancreatic cancer: a randomised controlled trial.[J].2001,358(9293).