You Position: Home > Paper
Risk factors for mortality of patients undergoing pancreaticoduodenectomy for periampullary carcinomas
( views:255, downloads:16 )
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF PANCREATOLOGY
- Issue:
- 4
- DOI:
- 10.3760/cma.j.issn.1674-1935.2005.04.007
- Key Word:
- 胰腺肿瘤;胰十二指肠切除术;危险因素
Abstract： 目的探讨影响胰十二指肠切除术治疗胰头和壶腹周围癌死亡的危险因素.方法对1995年1月至2004年6月期间行胰十二指肠切除术的196例胰头和壶腹周围癌患者的10项临床观察指标进行分析.结果术后并发症发生率为31.1%,病死率为5.6%.术前低蛋白血症( < 35 g/L)、高血糖( > 10 mmol/L)、术中出血量 > 1 000 ml、围手术期的APACHEⅡ评分 > 12和POSSUM评分 > 38时手术危险度较大,与手术死亡率呈正相关(P < 0.05).而年龄 > 65岁、手术时间超过6 h、术前血清胆红素 > 170μmol/L、黄疸持续时间 > 30 d、肿瘤 > 3 cm并不增加手术的病死率(P > 0.05).结论术前低蛋白血症,高血糖,出血量多及高APACHEⅡ和POSSUM分值是影响胰头十二指肠切除术死亡的高危因素.
- [1]张群华,倪泉兴,张延龄,等.应用APACHEⅡ和POSSUM评分指导胰腺癌患者外科治疗的临床分析[J].2001,(4).
- [2]C H, Su,Y M, Shyr,W Y, Lui,etc.Factors affecting morbidity, mortality and survival after pancreaticoduodenectomy for carcinoma of the ampulla of Vater.[J].1900,46.
- [3]K W, Millikan,D J, Deziel,J C, Silverstein,etc.Prognostic factors associated with resectable adenocarcinoma of the head of the pancreas.[J].1999,65(7).
- [4]Jones,HJ,de,Cossart-L.Risk scoring in surgical patients.[J].1999,86(2).
- [5]Khan AW,Davidson BR,Agarwal AK,etc.Evaluation of the POSSUM scoring system for comparative audit in pancreatic surgery.[J].2003,20(6).