Abstract： Objective:To summarize the application of hernia hook needle assisted laparoscopic gastrostomy in infants and to evaluate its clinical safety and efficacy.Methods:From January 2018 to January 2021, clinical data were retrospectively reviewed for 12 children(9 boys and 3 girls)undergoing laparoscopic gastrostomy with hernia repair needle.Median age was 113(22-337) days and median body weight (4 973±1 978) g. Descriptive statistical analysis was utilized for processing the relevant data of age, body weight, operative duration and postoperative complications.Results:Foley catheter was inserted in all cases.Median operative duration was (58.8±11.7) min, median postoperative initiating time of enteral feeding (4.0±1.4) days and median full enteral feeding time (12.3±4.0) days.During a postoperative follow-up period of (10-26) months, two children with rash around stoma improved after external application of stoma powder.One child developed gastric outlet obstruction from balloon blockage of pylorus due to tube shifting and the problem was resolved by replacing a gastric feeding tube.In 6 cases, Foley catheter was replaced by low-profile gastrostomy tube.And gastrostomy tube was removed in 8 cases and operative incision healed without surgical repair.The remaining 4 cases were all properly fixed and could rely on gastrostomy tube for enteral nutrition.There was no complications related to gastrostomy.Conclusions:Hernia hook needle assisted laparoscopic gastrostomy is a simple and safe technique.With better cosmetics due to minimal scar, it is worth a wider popularization.