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Advances in research on microRNA and radiosensitivity of non-small-cell lung cancer

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Author:: No author available

Journal Title:: Chinese Journal of Biomedical Engineering

Issue:: 2

DOI:: 10.3760/cma.j.cn115668-20200312-00053

Key Word:: 微RNAs;癌，非小细胞肺;放射疗法;辐射耐受性

Abstract：微RNA是一种单链非编码RNA，可调控基因表达，在肿瘤的发生发展中起到十分重要的作用。非小细胞肺癌（NSCLC）是肺癌最常见的病理类型，放疗是其最主要的治疗方式。然而临床中大量存在放疗抵抗现象，一定程度上限制了放疗的效果和发展。大量研究表明，微RNA可通过多种途径调控肿瘤放疗敏感性。本综述旨在探究微RNA与NSCLC放疗敏感性的关系，为临床NSCLC个性化放疗方案的制定提供理论依据和新的靶点。

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