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Obesity and hypertriglyceridemia:high risks for disease severity and mortality in COVID-19 patients

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Author:: No author available

Journal Title:: Acta Physiologica Sinica

Issue:: 5

DOI:: 10.13294/j.aps.2022.0080

Key Word:: 新型冠状病毒;脂质代谢;饮食;新型冠状病毒肺炎防治

Abstract：随着新型冠状病毒肺炎(简称"新冠肺炎")大流行进入第三个年头,大量数据显示肥胖和高甘油三酯血症是新冠肺炎重症和死亡的重要危险因素,并与新冠肺炎各种并发症密切相关.这些并发症包括急性呼吸衰竭、血栓栓塞、凝血功能障碍,以及细胞因子风暴等,是新冠肺炎重症和致死的最常见和最根本原因.本文综合分析了近3年来公开发表的来自世界各地、不同种族的关于新冠肺炎的临床报道和研究分析,得出新冠肺炎重症与肥胖和高甘油三酯血症之间存在临床关联的结论.在分析了各种关于新冠病毒研究结果的同时,我们还探讨了肥胖和高甘油三酯血症与新冠肺炎重症之间相关联的可能分子基础.我们也从公共健康的角度,提出了改善饮食和生活方式来应对新冠病毒对人类健康带来长期挑战的策略.

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