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Research progress of extracellular vesicles in the treatment of renal disease

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Author:: No author available

Journal Title:: Acta Physiologica Sinica

Issue:: 1

DOI:: 10.13294/j.aps.2022.0004

Key Word:: 细胞外囊泡;药物递送;干细胞;急性肾损伤;慢性肾脏病

Abstract：细胞外囊泡(extracellular vesicles,Evs)是细胞分泌的由脂质双分子层包绕形成的膜性囊泡,其内包含丰富的生物学信息,参与多种生理和病理过程.近年来,Evs在疾病治疗中也展现出了巨大应用前景,一方面来源于干细胞的Evs可以直接发挥治疗作用,另一方面Evs还可以作为一种天然的药物递送载体,为疾病的治疗提供新的给药策略.本文聚焦Evs在肾脏病治疗中的应用和研究进展.

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