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Regulation of vascular function by nitric oxide-related S-nitrosylation

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Author:: No author available

Journal Title:: Acta Physiologica Sinica

Issue:: 5

DOI:: 10.13294/j.aps.2017.0069

Key Word:: 一氧化氮;巯基亚硝基化;去亚硝基化;血管疾病;nitric oxide;S-nitrosylation;denitrosylation;cardiovascular disease

Abstract： Nitric oxide (NO),well known as the endothelium-derived relaxing factor (EDRF),has become increasingly recognized as an important determinant of cardiovascular diseases.A molecular pathway by which NO accomplishes various biochemical processes is the cGMP-independent post-translational modification of protein,S-nitrosylation.Here we review the biochemistry and regulating mechanisms of NO-related S-nitrosylation of proteins,and discuss the multiple roles of S-nitrosylation in vascular functions and pathology in particular.

Reference

[1].S-nitrosylation/Denitrosylation and Apoptosis of Immune Cells[J].2007,4(5).
[2]Selemidis, Stavros,Dusting, Gregory J.,Peshavariya, Hitesh,etc.Nitric oxide suppresses NADPH oxidase-dependent superoxide production by S-nitrosylation in human endothelial cells.[J].2007,75(2).
[3]Neil Hogg.The Kinetics of S-Transnitrosation-A Reversible Second-Order Reaction[J].1999,272(2).
[4]Jonathan S Stamler,Puneet Anand.Enzymatic mechanisms regulating protein S-nitrosylation: implications in health and disease.[J].2012,90(3).
[5]Ningling, Kang-Decker,Sheng, Cao,Suvro, Chatterjee,etc.Nitric oxide promotes endothelial cell survival signaling through S-nitrosylation and activation of dynamin-2.[J].2007,120.
[6]Stamler JS,Mu Y,Whalen EJ,etc.S-nitrosylation of beta-arrestin regulates beta-adrenergic receptor trafficking.[J].2008,31(3).
[7]Ley K,Mestas J.Monocyte-endothelial cell interactions in the development of atherosclerosis.[J].2008,18(6).
[8]McCarthy SA,Gordon SA,Abou-Jaoude W,etc.Nitric oxide induces murine thymocyte apoptosis by oxidative injury and a p53-dependent mechanism.[J].2001,70(1).
[9]P S, Tsao,R, Buitrago,J R, Chan,etc.Fluid flow inhibits endothelial adhesiveness. Nitric oxide and transcriptional regulation of VCAM-1.[J].1996,94.
[10]Jensen DE,Belka GK,Du-Bois GC.S-Nitrosoglutathione is a substrate for rat alcohol dehydrogenase class III isoenzyme.[J].1998,331(Pt.2).
[11]Michael S, Crane,Adriano G, Rossi,Ian L, Megson.A potential role for extracellular nitric oxide generation in cGMP-independent inhibition of human platelet aggregation: biochemical and pharmacological considerations.[J].2005,144(6).
[12]Matthew W, Foster,John R, Pawloski,David J, Singel,etc.Role of circulating S-nitrosothiols in control of blood pressure.[J].2005,45.
[13]Guala AS,Wouters EFM,Korn SH,etc.Nitric oxide represses inhibitory kB kinase through S-nitrosylation[J].2004,101(24).
[14]Zachary T, Kelleher,Akio, Matsumoto,Jonathan S, Stamler,etc.NOS2 regulation of NF-kappaB by S-nitrosylation of p65.[J].2007,282.
[15]Stamler JS,Benhar M,Forrester MT.Protein denitrosylation: enzymatic mechanisms and cellular functions.[J].2009,10(10).
[16]Rajib Sengupta,Brian S. Zuckerbraun,Stefan W. Ryter.Thioredoxin Catalyzes the Denitrosation of Low-Molecular Mass and Protein S-Nitrosothiols[J].2007,46(28).
[17]Bredt D S,Snyder S H.Nitric Oxide: A Physiologic Messenger Molecule[J].1994.
[18]Takuya Hatakeyama,Robert W. Hobson II,Peter J. Pappas,etc.Endothelial nitric oxide synthase regulates microvascular hyperpermeability in vivo[J].2006,574(1).
[19]Zhang G,Li Z,Marjanovic JA,etc.A platelet secretion pathway mediated by cGMP-dependent protein kinase.[J].2004,279(41).
[20]Smith Garvin JE,Jordan MS,Koretzky GA.T cell activation.[J].2009,27.
[21]Ghosh S,Karin M.Missing pieces in the NF-kappa B puzzle [Review][J].2002,109(Suppl).
[22]J S, Stamler,S, Lamas,F C, Fang.Nitrosylation. the prototypic redox-based signaling mechanism.[J].2001,106(6).
[23]Faubert D,Rautureau Y,Oubaha M,etc.S-nitrosylation of beta-catenin by eNOS-derived NO promotes VEGF-induced endothelial cell permeability.[J].2010,39(3).
[24]G, Kojda,D, Harrison.Interactions between NO and reactive oxygen species: pathophysiological importance in atherosclerosis, hypertension, diabetes and heart failure.[J].1999,43.
[25]Fabiola A, Sánchez,David D, Kim,Ricardo G, Durán,etc.Internalization of eNOS via caveolae regulates PAF-induced inflammatory hyperpermeability to macromolecules.[J].2008,295(4).
[26]Adriana V, Treuer,Daniel R, Gonzalez.Nitric oxide synthases, S-nitrosylation and cardiovascular health: from molecular mechanisms to therapeutic opportunities (review).[J].2015,11(3).
[27]Seinosuke, Kawashima,Mitsuhiro, Yokoyama.Dysfunction of endothelial nitric oxide synthase and atherosclerosis.[J].2004,24.
[28]Ibiza S,Victor VM,Bosca I,etc.Endothelial nitric oxide synthase regulates T cell receptor signaling at the immunological synapse.[J].2006,24(6).
[29]Pierre, Sonveaux,Andrew M, Kaz,Stacey A, Snyder,etc.Oxygen regulation of tumor perfusion by S-nitrosohemoglobin reveals a pressor activity of nitric oxide.[J].2005,96.
[30]Godoy LC,Moretti AI,Jurado MC,etc.Loss of CD40 endogenous S-nitrosylation during inflammatory response in endotoxemic mice and patients with sepsis.[J].2010,33(6).
[31]Kandasam, Ravi,Lisa A, Brennan,Snezana, Levic,etc.S-nitrosylation of endothelial nitric oxide synthase is associated with monomerization and decreased enzyme activity.[J].2004,101.
[32]Holmgren,A.,Sengupta,R..Thioredoxin and thioredoxin reductase in relation to reversible S-nitrosylation[J].2013,18(3).
[33]Anita, Guequén,Rodrigo, Carrasco,Patricia, Zamorano,etc.S-nitrosylation regulates VE-cadherin phosphorylation and internalization in microvascular permeability.[J].2016.
[34]Ma,K.,Lv,S.,Liu,B.,etc.CTLA4-IgG ameliorates homocysteine-accelerated atherosclerosis by inhibiting T-cell overactivation in apoE-/- mice[J].2013,97(2).
[35]Joan B. Mannick,Koichiro Asano,Kenneth Izumi,etc.Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation[J].1994,79(7).
[36]Stamler JS,Foster MW,McMahon TJ.S-nitrosylation in health and disease.[J].2003,9(4).
[37]Bredt DS.Endogenous nitric oxide synthesis: biological functions and pathophysiology.[J].1999,31(6).
[38]Zeng M,Liu L,Stamler JS,etc.An apoptotic model for nitrosative stress.[J].2000,39(5).
[39]Sun H,Wu MH,Moy AB,etc.Involvement of ROCK-mediated endothelial tension development in neutrophil-stimulated microvascular leakage.[J].2006,290(2).
[40]Murad F.Cyclic guanosine monophosphate as a mediator of vasodilation.[J].1986.
[41]Martinez-Ruiz A,Villanueva L,de Orduna CG,etc.S-nitrosylation of Hsp90 promotes the inhibition of its ATPase and endothelial nitric oxide synthase regulatory activities[J].2005,102(24).
[42]Michael A.Marietta,Phillip A.Erwin,Thomas Michel,etc.S-Nitrosation and Regulation of Inducible Nitric Oxide Synthase[J].2005,44(12).
[43]Stamler JS,Forrester MT,Foster MW.Assessment and application of the biotin switch technique for examining protein S-nitrosylation under conditions of pharmacologically induced oxidative stress.[J].2007,282(19).
[44]Tsikas D,Tewes KS,Raida M,etc.Inhibition of platelet aggregation by S-nitroso-cysteine via cGMP-independent mechanisms: evidence of inhibition of thromboxane A2 synthesis in human blood platelets.[J].1999,442(2/3).
[45]Simmons RL,Zhang XR,Ford HR,etc.Nitric oxide induces thymocyte apoptosis via a caspase-1-dependent mechanism.[J].2000,165(3).
[46]Stamler JS,Marshall HE.Inhibition of NF-kappa B by S-nitrosylation[J].2001,40(6).
[47]J R, Pawloski,D T, Hess,J S, Stamler.Export by red blood cells of nitric oxide bioactivity.[J].2001,409(6820).
[48]M A, Moro,R J, Russel,S, Cellek,etc.cGMP mediates the vascular and platelet actions of nitric oxide: confirmation using an inhibitor of the soluble guanylyl cyclase.[J].1996,93.
[49]J S, Stamler,O, Jaraki,J, Osborne,etc.Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin.[J].1992,89(16).
[50]Dimmeler S,Haendeler J,Tischler V,etc.Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69.[J].2002,4(10).
[51]Detcho A, Stoyanovsky,Yulia Y, Tyurina,Vladimir A, Tyurin,etc.Thioredoxin and lipoic acid catalyze the denitrosation of low molecular weight and protein S-nitrosothiols.[J].2005,127(45).
[52]M J, Hickey,K A, Sharkey,E G, Sihota,etc.Inducible nitric oxide synthase-deficient mice have enhanced leukocyte-endothelium interactions in endotoxemia.[J].1997,11.
[53]Paresh C, Sanghani,Wilhelmina I, Davis,Sharry L, Fears,etc.Kinetic and cellular characterization of novel inhibitors of S-nitrosoglutathione reductase.[J].2009,284(36).
[54]Takahama H,Sakuma I,Fujita M,etc.S-nitrosylated and pegylated hemoglobin, a newly developed artificial oxygen carrier, exerts cardioprotection against ischemic hearts.[J].2007,42(5).
[55]E S, Arnér,A, Holmgren.Physiological functions of thioredoxin and thioredoxin reductase.[J].2000,267.
[56]L, Jia,C, Bonaventura,J, Bonaventura,etc.S-nitrosohaemoglobin: a dynamic activity of blood involved in vascular control.[J].1996,380(6571).
[57]J S, Stamler,E J, Toone,S A, Lipton,etc.(S)NO signals: translocation, regulation, and a consensus motif.[J].1997,18(5).
[58]Dan E, Berkowitz,Ron, White,Dechun, Li,etc.Arginase reciprocally regulates nitric oxide synthase activity and contributes to endothelial dysfunction in aging blood vessels.[J].2003,108.
[59]Beuve A,Sayed N,Duran WN,etc.Nitroglycerin-induced S-nitrosylation and desensitization of soluble guanylyl cyclase contribute to nitrate tolerance.[J].2008,103(6).
[60]Judith, Haendeler,J?rg, Hoffmann,Andreas M, Zeiher,etc.Antioxidant effects of statins via S-nitrosylation and activation of thioredoxin in endothelial cells: a novel vasculoprotective function of statins.[J].2004,110.
[61]Benhar M,Hess DT,Stamler JS,etc.Regulated protein denitrosylation by cytosolic and mitochondrial thioredoxins.[J].2008,320(5879).
[62]Robin E, Gandley,Vladimir A, Tyurin,Wan, Huang,etc.S-nitrosoalbumin-mediated relaxation is enhanced by ascorbate and copper: effects in pregnancy and preeclampsia plasma.[J].2005,45.
[63].S-nitrosothiols and the S-nitrosoproteome of the cardiovascular system[J].2013,18(3).
[64]Anthony R, White,Sungwoo, Ryoo,Dechun, Li,etc.Knockdown of arginase I restores NO signaling in the vasculature of old rats.[J].2006,47.
[65]Dejana,E.,Orsenigo,F..Endothelial adherens junctions at a glance[J].2013,126(12).
[66]Erin J, Whalen,Matthew W, Foster,Akio, Matsumoto,etc.Regulation of beta-adrenergic receptor signaling by S-nitrosylation of G-protein-coupled receptor kinase 2.[J].2007,129.
[67]Kenji Matsushita,William M. Baldwin III,Wolfgang Bergmeier,etc.Regulation of platelet granule exocytosis by S-nitrosylation[J].2005,102(10).
[68]Lakshmi, Santhanam,Hyun Kyo, Lim,Hyun Kyoung, Lim,etc.Inducible NO synthase dependent S-nitrosylation and activation of arginase1 contribute to age-related endothelial dysfunction.[J].2007,101.
[69]Vujaskovic Z,Li CY,Li F,etc.Regulation of HIF-1alpha stability through S-nitrosylation.[J].2007,26(1).
[70]Raynard L, Bateman,Daniel, Rauh,Brandon, Tavshanjian,etc.Human carbonyl reductase 1 is an S-nitrosoglutathione reductase.[J].2008,283.
[71]Shahani N,Dawson TM,Kornberg MD,etc.Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis.[J].2008,10(7).
[72]Limin Liu,Yun Yan,Ming Zeng,etc.Essential Roles of S-Nitrosothiols in Vascular Homeostasis and Endotoxic Shock[J].2004,116(4).
[73]Huber H,Kroncke KD,Wahn V,etc.Nitric oxide induces apoptosis in mouse thymocytes.[J].1995,155(6).
[74]Kenji Matsushita,Craig N. Morrell,Beatrice Cambien,etc.Nitric Oxide Regulates Exocytosis by S-Nitrosylation of N-ethylmaleimide-Sensitive Factor[J].2003,115(2).
[75]Hurley TD,Yang ZN,Bosron WF.Structure of human chi chi alcohol dehydrogenase: a glutathione-dependent formaldehyde dehydrogenase[J].1997,265(3).
[76]Jens Kroll,Johannes Waltenberger.VEGF-A Induces Expression of eNOS and iNOS in Endothelial Cells via VEGF Receptor-2 (KDR)[J].1998,252(3).
[77]Marín,N.,Meininger,C.J.,Quezada,C.,etc.S-Nitrosation of β-catenin and p120 catenin: A novel regulatory mechanism in endothelial hyperpermeability[J].2012,111(5).
[78]Hogg N,Zhang Y.Formation and stability of S-nitrosothiols in RAW 264.7 cells.[J].2004,287(3).
[79]Scalia R,Baines A,Jones SP,etc.Leukocyte-endothelial cell interactions in nitric oxide synthase-deficient mice.[J].1999,276(6 Pt.2).
[80]Diesen DL,Hess DT,Stamler JS.Hypoxic vasodilation by red blood cells: evidence for an s-nitrosothiol-based signal.[J].2008,103(5).
[81]Hester LD,Kim SF,Fujimuro M,etc.S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding[J].2005,7(7).
[82]Benhar, Moran.Nitric oxide and the thioredoxin system: a complex interplay in redox regulation[J].2015,1850(12).
[83]Papapetropoulos A,Garc\u00eda-Carde\u00f1a G,Madri J A,etc.Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells.[J].1997.
[84]Patterson, C,Wu, YX,Ferguson, JE,etc.SDF-1 alpha stimulates JNK3 activity via eNOS-dependent nitrosylation of MKP7 to enhance endothelial migration[J].2009,106(14).
[85]Vallance P.S-nitrosylation of dimethylarginine dimethylaminohydrolase regulates enzyme activity: Further interactions between nitric oxide synthase and dimethylarginine dimethylaminohydrolase.[J].2002,99(21).
[86]Whalen EJ,Johnson AK,Lewis SJ.Beta-adrenoceptor dysfunction after inhibition of NO synthesis.[J].2000,36(3).
[87]Lima, Brian,Lam, Gregory K. W.,Liang Xie,etc.Endogenous S-nitrosothiols protect against myocardial injury.[J].2009,106(15).
[88]Lima B,Hess D,Forrester MT.S-nitrosylation in cardiovascular signaling.[J].2010,106(4).
[89]Kim YM.,Talanian RV.,Billiar TR..Nitric Oxide Inhibits Apoptosis by Preventing Increases in Caspase-3-Like Activity via Two Distinct Mechanisms[J].1997,272(49).
[90]F?rstermann,U.,Sessa,W.C..Nitric oxide synthases: Regulation and function[J].2012,33(7).
[91]Zhang, Qin,Zeng, Xiaokun,Guo, Jingxuan,etc.Oxidant stress mechanism of homocysteine potentiating Con A-induced proliferation in murine splenic T lymphocytes.[J].2002,53(4).
[92]Ratcliffe PJ,Pugh CW.Regulation of angiogenesis by hypoxia: role of the HIF system.[J].2003,9(6).
[93]Piccinini G,Remuzzi G,Sayegh MH,etc.Thymic dendritic cells express inducible nitric oxide synthase and generate nitric oxide in response to self- and alloantigens.[J].2000,164(9).
[94]Irwin C,Roberts W,Naseem KM.Nitric oxide inhibits platelet adhesion to collagen through cGMP-dependent and independent mechanisms: the potential role for S-nitrosylation.[J].2009,20(7).
[95]Hogg,N.Biological chemistry and clinical potential of S-nitrosothiols.[J].2000,28(10).
[96]Fenyo,I.M.,Gafencu,A.V..The involvement of the monocytes/macrophages in chronic inflammation associated with atherosclerosis[J].2013,218(11).
[97]Gow AJ,Chen Q,Hess DT,etc.Basal and stimulated protein S-nitrosylation in multiple cell types and tissues.[J].2002,277(12).
[98]N, Sogo,K S, Magid,C A, Shaw,etc.Inhibition of human platelet aggregation by nitric oxide donor drugs: relative contribution of cGMP-independent mechanisms.[J].2000,279(2).
[99]A, Holmgren.Thioredoxin and glutaredoxin systems.[J].1989,264.
[100]L, Liu,A, Hausladen,M, Zeng,etc.A metabolic enzyme for S-nitrosothiol conserved from bacteria to humans.[J].2001,410(6827).
[101]Forrester, Michael T.,Moseley, M. Arthur,Foster, Matthew W.,etc.Proteomic analysis of S-nitrosylation and denitrosylation by resin-assisted capture[J].2009,27(6).
[102]Michael G, Espey,Katrina M, Miranda,Douglas D, Thomas,etc.A chemical perspective on the interplay between NO, reactive oxygen species, and reactive nitrogen oxide species.[J].2002,962.
[103]B V, Khan,D G, Harrison,M T, Olbrych,etc.Nitric oxide regulates vascular cell adhesion molecule 1 gene expression and redox-sensitive transcriptional events in human vascular endothelial cells.[J].1996,93.
[104]David J, Singel,Jonathan S, Stamler.Blood traffic control.[J].2004,430(6997).
[105]Benoit MO,Drueke TB,Massy ZA,etc.Increased pasma S-nitrosothiol concentrations predict cardiovascular outcomes among patients with end-stage renal disease: a prospective study.[J].2004,15(2).
[106]David J, Singel,Jonathan S, Stamler.Chemical physiology of blood flow regulation by red blood cells: the role of nitric oxide and S-nitrosohemoglobin.[J].2005,67.
[107]X G, Tai,K, Toyo-oka,N, Yamamoto,etc.Expression of an inducible type of nitric oxide (NO) synthase in the thymus and involvement of NO in deletion of TCR-stimulated double-positive thymocytes.[J].1997,158.
[108]Charles J, Lowenstein.Nitric oxide regulation of protein trafficking in the cardiovascular system.[J].2007,75(2).
[109]Peluffo G,Trujillo M,Freeman BA,etc.Xanthine oxidase-mediated decomposition of S-nitrosothiols.[J].1998,273(14).
[110]Alexander Y, Kots,Emil, Martin,Iraida G, Sharina,etc.A short history of cGMP, guanylyl cyclases, and cGMP-dependent protein kinases.[J].2009,(191).
[111]J R, Pawloski,R V, Swaminathan,J S, Stamler.Cell-free and erythrocytic S-nitrosohemoglobin inhibits human platelet aggregation.[J].1998,97.
[112]Jin, Qian,David, Fulton.Post-translational regulation of endothelial nitric oxide synthase in vascular endothelium.[J].2013,4.
[113]Gould,N.,Doulias,P.-T.,Tenopoulou,M.,etc.Regulation of protein function and signaling by reversible cysteine s-nitrosylation[J].2013,288(37).
[114]V M, Bolotina,S, Najibi,J J, Palacino,etc.Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle.[J].1994,368(6474).
[115]J B, Mannick,A, Hausladen,L, Liu,etc.Fas-induced caspase denitrosylation.[J].1999,284.
[116]Kharitonov VG,Sundquist AR,Sharma VS.Kinetics of nitrosation of thiols by nitric oxide in the presence of oxygen.[J].1995,270(47).
[117]V A, Tyurin,S X, Liu,Y Y, Tyurina,etc.Elevated levels of S-nitrosoalbumin in preeclampsia plasma.[J].2001,88.
[118]Foerstermann, Ulrich,Xia, Ning,Li, Huige.Roles of Vascular Oxidative Stress and Nitric Oxide in the Pathogenesis of Atherosclerosis[J].2017,120(4).
[119].The role of thioredoxin in the regulation of cellular processes by S-nitrosylation[J].2012,1820(6).
[120]Espey MG,Thomas DD,Miranda KM,etc.Focusing of nitric oxide mediated nitrosation and oxidative nitrosylation as a consequence of reaction with superoxide.[J].2002,99(17).
[121]Hansson GK,Hermansson A.The immune system in atherosclerosis.[J].2011,12(3).
[122]Brian C. Smith,Nathaniel B. Fernhoff,Michael A. Marletta.Mechanism and Kinetics of Inducible Nitric Oxide Synthase Auto-S-nitrosation and Inactivation[J].2012,51(5).
[123]Vadim V, Sumbayev,Andreja, Budde,Jie, Zhou,etc.HIF-1 alpha protein as a target for S-nitrosation.[J].2003,535.