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- Author:
- No author available
- Journal Title:
- Acta Physiologica Sinica
- Issue:
- 3
- DOI:
- 10.13294/j.aps.2016.0047
- Key Word:
- @@
Abstract： 上世纪90年代生命科学“组学”浪潮迭起,国际生理科学联合会(International Union of Physiological Sciences,IUPS)与时俱进,提出了“生理组计划(Physiome Project)”,由此,生理组学(physiomics)这一概念应运而生.生理组学指综合运用生物、数学与计算机技术,整合基因及蛋白质等分子生物学信息,构建量化数学模型,以定量描述机体在细胞、器官及系统等各个层次的功能、调控机制及相互联系,更精准地阐明机体功能调控及其与环境变化相适应的机制.相比于经典生理学,生理组学的主要特征是引入现代交叉学科相关技术和成果,将机体器官视为一非线性系统,对其解剖结构可视化、生理活动建模量化.生理组学研究不仅为生理学带来了新的技术和思路,还促进了生理学与当今生命科学相关学科的交叉融合,为经典生理学增添了新的活力.
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