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Evaluation of effects of sleep disorders on anxiety, depression,and lower gastrointestinal symptoms in elderly patients with functional dyspepsia based on brain-intestinal axis theory
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- Author:
- No author available
- Journal Title:
- World Chinese Journal of Digestology
- Issue:
- 8
- DOI:
- 10.11569/wcjd.v28.i8.280
- Key Word:
- 老年;功能性消化不良;睡眠障碍;焦虑;抑郁;下消化道症状
Abstract： 背景 功能性消化不良(functional dyspepsia,FD)是老年患者常见疾病之一,病情容易反复,严重影响患者身心健康.肠-脑互动异常是FD发病主要病因,大多伴有不同程度的睡眠障碍和焦虑、抑郁等负面心理.目前,对于老年FD患者与睡眠障碍和焦虑抑郁、下消化道症状的研究报道较少,目的基于脑-肠轴学说探讨观察老年FD患者睡眠障碍对焦虑抑郁和下消化道症状影响分析.方法选择2017-02/2019-09在我院就诊的236例老年FD患者为研究对象,课题负责人发放量表,对符合罗马Ⅳ标准的老年FD患者进行调查,评估其下消化道症状严重程度,睡眠质量和焦虑和抑郁评分变化情况.结果214例老年FD患者中存在睡眠障碍者103例(48.13％),存在焦虑、抑郁者182例(85.05％).有睡眠障碍老年FD患者的下腹痛发生率为35.92％,下腹不适(非疼痛)发生率为33.98％、羊粪样或硬便发生率为21.36％、用劲排便发生率为32.04％、排便不尽感发生率为43.69％和便急感的发生率为27.18％,均高于无睡眠障碍老年FD患者,差异比较均有统计学意义(P＜0.05).有睡眠障碍的老年FD睡眠障碍患者焦虑自评量表评分为65.34分±7.29分,抑郁自评量表评分为66.17分±8.26分,均高于无睡眠障碍的老年FD患者(P＜0.05).结论老年FD患者常同时存在睡眠障碍与焦虑、抑郁,睡眠障碍与老年FD患者的下消化道症状关系密切.
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