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Biological role of microRNA-146a

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Author:: No author available

Journal Title:: World Chinese Journal of Digestology

Issue:: 18

DOI:: 10.11569/wcjd.v27.i18.1155

Key Word:: MicroRNA-146a;生物学作用;综述

Abstract： MicroRNA是一种内源性单链非编码小分子RNA,通过与靶mRNA的特异性结合,以降解mRNA或阻碍其翻译从而在转录后水平调节靶mRNA的表达.MicroRNA-146a参与机体的多种生物学过程,具有多种生物学功能.本文将从其控制炎症反应,调节免疫,介导髓样细胞增殖以及肿瘤发生发展等几个方面进行综述.

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