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Gastric microflora and gastric disease

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Author:: No author available

Journal Title:: World Chinese Journal of Digestology

Issue:: 18

DOI:: 10.11569/wcjd.v27.i18.1149

Key Word:: 胃内微生物群;幽门螺杆菌;胃部疾病;萎缩性胃炎;消化性溃疡;胃癌

Abstract：长期以来,学术界认为胃内是无菌的环境,但1982年幽门螺杆菌(Helicobacter pylori,H.pylori)的发现改变了这一概念.在过去的几十年里,检测方法从传统的细菌培养,到宏基因组高通量测序技术的应用,这些现代技术为洞察胃内的微生物群落、分析群落间的相互作用提供了支持.H.pylori是胃部疾病重要的危险因素,但可能还有别的菌群也参与了胃部疾病的发生.本文就目前有关胃微生物群与胃部疾病的相互关系的研究进展作一综述,旨从微生态角度对胃部疾病的防治策略提供新的思路.

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