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Staging of liver fibrosis using Gd-EOB-DTPA and Gd-BOPTA enhanced magnetic resonance imaging

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Author:: No author available

Journal Title:: World Chinese Journal of Digestology

Issue:: 33

DOI:: 10.11569/wcjd.v26.i33.1907

Key Word:: 肝纤维化;磁共振;莫迪司;普美显

Abstract：肝硬化的严重程度与临床治疗密切相关,因此,对肝纤维化进行准确分期尤为重要.穿刺活检虽然能对肝硬化程度进行准确分期,因其为有创检查,在临床应用中有一定的限制.临床磁共振(magnetic resonance image,MRI)检查已常规用于肝脏疾病的诊断.近年来,两种新型对比剂莫迪司和普美显已成功用于肝脏成像,可以无创地用于肝纤维化分期以及肝功能的评估,肝功能不同程度的肝硬化患者的肝实质强化程度具有统计学差异.本文将近十年来莫迪司、普美显增强MRI用于评估肝纤维化分期的研究现状与进展进行简要综述.

Reference

[1]丁莺,曾蒙苏,饶圣祥,等.肝细胞特异性对比剂钆塞酸二钠增强磁共振检查对非酒精性脂肪肝诊断及分级的潜在价值[J].2015,(4).
[2]张涛,陆健,张学琴,等.钆塞酸二钠MR肝胆期对肝硬化背景下肝癌的诊断价值[J].2014,(7).
[3]Daire, Jean-Luc,Leporq, Benjamin,Vilgrain, Valerie,etc.Liver Perfusion Modifies Gd-DTPA and Gd-BOPTA Hepatocyte Concentrations Through Transfer Clearances Across Sinusoidal Membranes[J].2017,42(4).
[4]Tamada, T.,Tanimoto, D.,Kanki, A.,etc.Hepatic parenchymal enhancement at Gd-EOB-DTPA-enhanced MR imaging: Correlation with morphological grading of severity in cirrhosis and chronic hepatitis[J].2012,30(3).
[5]Xiu-Mei Li,Zhu Chen,En-Hua Xiao,etc.Diagnostic value of gadobenate dimeglumine-enhanced hepatocyte-phase magnetic resonance imaging in evaluating hepatic fibrosis and hepatitis[J].2017,(17).
[6]Tsuda N,Matsui O.Signal profile on Gd-EOB-DTPA-enhanced MR imaging in non-alcoholic steatohepatitis and liver cirrhosis induced in rats: correlation with transporter expression.[J].2011,21(12).
[7]Wei, Zhang,Xiang, Kong,Zhen J, Wang,etc.Dynamic Contrast-Enhanced Magnetic Resonance Imaging with Gd-EOB-DTPA for the Evaluation of Liver Fibrosis Induced by Carbon Tetrachloride in Rats.[J].2015,10.
[8]Tomohiro, Sato,Tsutomu, Tamada,Shigeru, Watanabe,etc.Tissue gadolinium deposition in hepatorenally impaired rats exposed to Gd-EOB-DTPA: evaluation with inductively coupled plasma mass spectrometry (ICP-MS).[J].2015,120(6).
[9]Blomqvist L,Douglas L,Jonas E,etc.Assessment of liver function in primary biliary cirrhosis using Gd-EOB-DTPA-enhanced liver MRI.[J].2010,12(8).
[10]Nakayama, T.,Yoshiura, T.,Nishie, A.,etc.Balanced MR cholangiopancreatography with motion-sensitised driven-equilibrium (MSDE) preparation: feasibility of Gd-EOB-DTPA-enhanced biliary examination[J].2016,71(12).
[11]Kashiwagi, Yuto,Rokugawa, Takemi,Watabe, Hiroshi,etc.Gd-EOB-DTPA-enhanced-MR imaging in the inflammation stage of nonalcoholic steatohepatitis (NASH) in mice[J].2016,34(6).
[12]Fujita,N.,Nishie,A.,Takayama,Y.,etc.MR prediction of liver fibrosis using a liver-specific contrast agent: Superparamagnetic iron oxide versus Gd-EOB-DTPA[J].2012,36(3).
[13]Pastor, C.M..Hepatic parenchymal enhancement at Gd-EOB-DTPA-enhanced MR imaging: Correlation with morphological grading of severity in cirrhosis chronic hepatitis[J].2012,30(10).
[14]Haimerl, Michael,Verloh, Niklas.Assessment of Clinical Signs of Liver Cirrhosis Using T1 Mapping on Gd-EOB-DTPA-Enhanced 3T MRI.[J].2013,8(12).
[15]Okada M,Murakami T,Tsuda N.New proposal for the staging of nonalcoholic steatohepatitis: evaluation of liver fibrosis on Gd-EOB-DTPA-enhanced MRI.[J].2010,73(1).
[16]Choi,J.Y.,Yoon,S.K.,Lee,Y.J.,etc.Clinical factors predictive of insufficient liver enhancement on the hepatocyte-phase of Gd-EOB-DTPA-enhanced magnetic resonance imaging in patients with liver cirrhosis[J].2013,48(10).
[17]N, Verloh,M, Haimerl,J, Rennert,etc.Impact of liver cirrhosis on liver enhancement at Gd-EOB-DTPA enhanced MRI at 3 Tesla.[J].2013,82(10).
[18]Michael, Haimerl,Irene, Fuhrmann,Stefanie, Poelsterl,etc.Gd-EOB-DTPA-enhanced T1 relaxometry for assessment of liver function determined by real-time 13C-methacetin breath test.[J].2018,(Spec ).
[19]Shi-Hong Ying,Xiao-Dong Teng,Zhao-Ming Wang,etc.Gd-EOB-DTPA-enhanced magnetic resonance imaging for bile duct intraductal papillary mucinous neoplasms[J].2015,(25).
[20]Xie, Sheng,Sun, Yongliang,Wang, Lei,etc.Assessment of Liver Function and Liver Fibrosis with Dynamic Gd-EOB-DTPA Enhanced MRI[J].2015,22(4).
[21]Jian-Wei Wu,Yue-Cheng Yu,Xian-Li Qu,etc.Optimization of hepatobiliary phase delay time of Gd-EOB-DTPA-enhanced magnetic resonance imaging for identification of hepatocellular carcinoma in patients with cirrhosis of different degrees of severity[J].2018,(3).
[22]Hata, Hirofumi,Inoue, Yusuke,Nakajima, Ai,etc.Influence of the Magnetic Field Strength on Image Contrast in Gd-EOB-DTPA-enhanced MR Imaging: Comparison between 1.5T and 3.0T[J].2017,16(2).
[23]Atsushi Higaki,Katsuyoshi Ito,Tsutomu Tamada,etc.Prognosis of small hepatocellular nodules detected only at the hepatobiliary phase of Gd-EOB-DTPA-enhanced MR imaging as hypointensity in cirrhosis or chronic hepatitis[J].2014,24(10).
[24]Jung, Jinhong,Yoon, Sang Min,Cho, Byungchul,etc.Hepatic reaction dose for parenchymal changes on Gd-EOB-DTPA-enhanced magnetic resonance images after stereotactic body radiation therapy for hepatocellular carcinoma[J].2016,60(1).
[25]Zhang, Weiguo,Wang, Xiao,Miao, Youhan,etc.Liver function correlates with liver-to-portal vein contrast ratio during the hepatobiliary phase with Gd-EOB-DTPA-enhanced MR at 3 Tesla[J].2018,43(9).
[26]Lee, Jei Hee,Kim, Bohyun,Kim, Hye Jin,etc.High spatial resolution navigated 3D T1-weighted hepatobiliary MR cholangiography using Gd-EOB-DTPA for evaluation of biliary anatomy in living liver donors[J].2018,43(7).
[27]Tohru Utsunomiya,Mitsuo Shimada,Jun Hanaoka,etc.Possible utility of MRI using Gd-EOB-DTPA for estimating liver functional reserve.[J].2012,47(4).
[28]Ngu, Sharon,Lebron-Zapata, Lizza,Pomeranz, Christy,etc.Inter-observer agreement on the assessment of relative liver lesion signal intensity on hepatobiliary phase imaging with gadoxetate (Gd-EOB-DTPA)[J].2016,41(1).
[29]Sheng, Ruo Fan,Wang, He Qing,Yang, Li,etc.Assessment of liver fibrosis using T1 mapping on Gd-EOB-DTPA-enhanced magnetic resonance[J].2017,49(7).
[30]Lee, Yedaun,Kim, So Yeon,Kim, Kyoung Won,etc.Contrast-enhanced MR cholangiography with Gd-EOB-DTPA for preoperative biliary mapping: correlation with intraoperative cholangiography[J].2015,56(7).
[31]Mamone, Giuseppe,Marrone, Gianluca,Caruso, Settimo,etc.Intrahepatic mass-forming cholangiocarcinoma: enhancement pattern on Gd-BOPTA-MRI with emphasis of hepatobiliary phase[J].2015,40(7).
[32]Kim, B.H.,Park, Y.S.,Kim, K.A.,etc.Using Gd-EOB-DTPA-enhanced 3-T MRI for the differentiation of infiltrative hepatocellular carcinoma and focal confluent fibrosis in liver cirrhosis[J].2013,31(7).
[33]Jeon, Inhwan,Cho, Eun-Suk,Kim, Joo Hee,etc.Feasibility of 10-Minute Delayed Hepatocyte Phase Imaging Using a 30�� Flip Angle in Gd-EOB-DTPA-Enhanced Liver MRI for the Detection of Hepatocellular Carcinoma in Patients with Chronic Hepatitis or Cirrhosis.[J].2016,(12).
[34]Granata, Vincenza,Catalano, Orlando,Fusco, Roberta,etc.The target sign in colorectal liver metastases: an atypical Gd-EOB-DTPA "uptake" on the hepatobiliary phase of MR imaging[J].2015,40(7).
[35]Inoue, Tatsuo,Hyodo, Tomoko,Korenaga, Keiko,etc.Kupffer phase image of Sonazoid-enhanced US is useful in predicting a hypervascularization of non-hypervascular hypointense hepatic lesions detected on Gd-EOB-DTPA-enhanced MRI: a multicenter retrospective study[J].2016,51(2).
[36]徐瑞,常江,黄华,等.慢性乙型肝炎患者临床指标与肝脏纤维化程度关系及明显肝纤维化危险因素的Logistic回归分析[J].2016,(2).
[37]C C, Xu,Y F, Tang,X Z, Ruan,etc.The value of Gd-BOPTA- enhanced MRIs and DWI in the diagnosis of intrahepatic mass-forming cholangiocarcinoma.[J].2017,64(6).
[38]Ma,C.,Liu,A.,Wang,Y.,etc.The hepatocyte phase of Gd-EOB-DTPA-enhanced MRI in the evaluation of hepatic fibrosis and early liver cirrhosis in a rat model: An experimental study[J].2014,108(2).
[39]Lee, Sunyoung,Choi, Dongil,Jeong, Woo Kyoung.Hepatic enhancement of Gd-EOB-DTPA-enhanced 3 Tesla MR imaging: Assessing severity of liver cirrhosis[J].2016,44(5).
[40]Higaki,A.,Ito,K.,Tamada,T.,etc.High-risk nodules detected in the hepatobiliary phase of Gd-EOB-DTPA-enhanced mr imaging in cirrhosis or chronic hepatitis: Incidence and predictive factors for hypervascular transformation, preliminary results[J].2013,37(6).
[41]Golfieri R,Renzulli M,Lucidi V,etc.Contribution of the hepatobiliary phase of Gd-EOB-DTPA-enhanced MRI to Dynamic MRI in the detection of hypovascular small (</= 2 cm) HCC in cirrhosis.[J].2011,21(6).
[42]Liu, Qingwei,Zhao, Xinya,Zhu, Qiang,etc.The relationship between liver function and liver parenchymal contrast enhancement on Gd-BOPTA-enhanced MR imaging in the hepatocyte phase[J].2015,33(6).
[43]Zhang, Zhong-wei,Xiao, Xin-lan,Cai, Jing,etc.Preclinical evaluation of severely defective manganese-based nanocrystal as a liver-specific contrast media for MR imaging: comparison with Gd-EOB-DTPA and MnDPDP[J].2018,29(22).
[44]Kakales I,Petrowsky H,Marincek B,etc.Contrast-enhanced MR cholangiography with Gd-EOB-DTPA in patients with liver cirrhosis: visualization of the biliary ducts in comparison with patients with normal liver parenchyma.[J].2008,18(8).