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Molecular targets regulating invasion and metastasis of pancreatic cancer

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Author:: No author available

Journal Title:: World Chinese Journal of Digestology

Issue:: 28

DOI:: 10.11569/wcjd.v26.i28.1651

Key Word:: 胰腺癌;侵袭;转移;分子靶点;调控机制

Abstract：胰腺癌是恶性程度最高的消化道肿瘤之一.侵袭和转移是胰腺癌的重要生物学特性,也是导致胰腺癌预后不良的重要因素.近年来,大量研究证明多种分子、基因和蛋白参与调控胰腺癌细胞的侵袭和转移,因此,深入揭示和研究胰腺癌侵袭转移的分子机制,不仅有助于发现新的肿瘤标志物和胰腺癌早期诊断,还可以用来制定新的有效治疗策略以及判断预后.本文就影响胰腺癌侵袭和转移的分子靶点和机制的最新进展作一综述.

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