Abstract： AIM To observe the influence of graphic health education on elderly patients undergoing endoscopic retrograde cholangiopancreatography METHODS One thousand and two hundred elderly patients who underwent ERCP at our hospital from January 2016 to June 2017 were selected and randomly divided into either a control group or an observation group,with 600 cases in each group.Both groups were given routine nursing care,and the observation group was additionally given graphic health education.The physiological indexes,Self-rating Anxiety Scale (SAS) score,Self-rating Depression Scale (SDS) score,Visual Analogue Scale (VAS) score,and nursing satisfaction degree were compared between the two groups.RESULTS Diastolic blood pressure,systolic blood pressure,heart rate,and respiratory rate were significantly lower in the observation group than in the control group (P ＜ 0.05).Before the intervention,SAS,SDS,and VAS scores were similar between the two groups.After intervention,SAS,SDS,and VAS scores were significantly lower in the observation group than in the control group (P ＜ 0.05).The percentages of patients with knowledge on the disease,diet,activity,drugs,and other ERCP related aspects were significantly higher in the observation group than in the control group (P ＜ 0.05).The education time was significantly shorter and the nursing satisfaction rate was significantly higher in the observation group than in the control group (P ＜ 0.05),although the complication rates of the two groups was similar.CONCLUSION Graphic health education among elderly patients undergoing ERCP can significantly relieve anxiety,reduce physiological index fluctuations,and improve patients' health knowledge level and nursing satisfaction.