Abstract： AIM To observe the effect of WeChat platform-based nursing care on digestive system symptoms and care burden of primary caregivers of patients with lung cancer on chemotherapy.METHODS Eighty primary caregivers of patients with lung cancer on chemotherapy were selected and randomly divided into either a control group or an observation group,with 40 cases in each group.Both groups were given psychological nursing,diet nursing,health education and stress-relieving measures.The observation group was additionally given WeChat platform-based nursing care.The digestive system symptom scores and the care burden score were compared between the two groups.RESULTS The scores of abdominal distention,early satiation,belching,nausea and appetite were significantly lower in the observation group than in the control group (P ＜ 0.05).There was no significant difference between the two groups in the care burden score before intervention.After intervention,the care burden score decreased significantly in both two groups (P ＜ 0.05),and the decrease was more significant in the observation group than in the control group (P ＜ 0.05).CONCLUSION WeChat platform-based nursing care can reduce digestive system symptom scores and care burden score of primary caregivers of patients with lung cancer on chemotherapy.