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Treatment of infants with bacterial pneumonia and diarrhea: Clinical efficacy and impact on immune cells

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Author:
No author available
Journal Title:
World Chinese Journal of Digestology
Issue:
31
DOI:
10.11569/wcjd.v24.i31.4311
Key Word:
婴幼儿细菌性肺炎;腹泻;治疗方法;免疫细胞;流式细胞仪;Bacterial pneumonia;Diarrhea;Treatment;Immune cells;Flow cytometry

Abstract´╝Ü 目的 观察婴幼儿细菌性肺炎合并腹泻治疗方法及对免疫细胞的影响,为临床提供依据.方法 选取2015-01/2016-07诊治的婴幼儿细菌性肺炎合并腹泻患儿60例,根据治疗方案不同分为对照组(n=30)和观察组(n=30).对照组采用乳酸菌片治疗,观察组联合思密达治疗,采用流式细胞仪检测免疫指标,比较2组临床疗效及对细胞免疫的影响.结果 观察组治疗7 d疗效率显著高于对照组(93.33% vs 70.00%,P<0.05);观察组大便次数正常、大便性状正常、实验室指标正常及临床症状消失时间,显著短于对照组(P<0.05);观察组治疗后细胞免疫功能水平IgM、IgG及IgA,显著高于对照组(P<0.05).结论 婴幼儿细菌性肺炎合并腹泻患儿在乳酸菌片基础上联合思密达治疗效果理想,能提高患儿T淋巴细胞亚群水平,值得推广应用.

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